Results 141 to 150 of about 149,065 (306)

Polymyalgia Rheumatica After COVID-19 Vaccination: Data from the EudraVigilance Database

open access: yesActa Médica Portuguesa
N/a.
Cláudia Pinto Oliveira   +4 more
doaj   +1 more source

Under-reporting of Adverse Drug Reactions: The Need for an Automated Reporting System

open access: yesRevue interdisciplinaire des sciences de la santé - Interdisciplinary Journal of Health Sciences, 2013
Although upwards of 32,000 adverse drug reactions are reported to Health Canada annually, this represents only approximately 5% of cases experienced by Canadians every year. This gross display of underreporting not only results in unrepresentative data in regards to adverse drug reactions, but further discredits databases used by healthcare ...
openaire   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

open access: yesAdvanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim   +5 more
wiley   +1 more source

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

open access: yesAdvanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu   +6 more
wiley   +1 more source

Social media mining for identification and exploration of health-related information from pregnant women [PDF]

open access: yes, 1989
Widespread use of social media has led to the generation of substantial amounts of information about individuals, including health-related information.
Chandrashekar, Pramod Bharadwaj   +3 more
core   +3 more sources

An Edible H2O2 Biosensor for Gastrointestinal Metabolites and Peroxidase Enzyme Quantification

open access: yesAdvanced Healthcare Materials, EarlyView.
We present an edible biosensor for gastric fluid analysis that integrates a caffeic acid–horseradish peroxidase redox system into an edible electrolyte‐gated transistor. The device enables rapid, low‐volume detection of H2O2 and, with minimal modification, metabolites and enzyme activity in simulated gastrointestinal conditions.
Valerio Francesco Annese   +10 more
wiley   +1 more source

Pharmacovigilance in clinical trials [PDF]

open access: yesVojnosanitetski Pregled, 2007
Ilić Katarina, Ugrešić Nenad
doaj   +1 more source

Safety evaluation of selective estrogen receptor degraders (SERDs) using real-world evidence from the FDA Adverse Event Reporting System (FAERS)

open access: yesScientific Reports
This study aims to evaluate post-marketing adverse event data for two selective estrogen receptor degraders (SERDs) in a real-world context, identify potential risk signals, and offer insights for clinical pharmacovigilance.
Ye Kang   +3 more
doaj   +1 more source

Laser‐Assisted Processing and Modification of Bioactive Glasses: A Review

open access: yesAdvanced Healthcare Materials, EarlyView.
Laser technologies provide powerful tools to process and transform bioactive glasses for advanced biomedical applications. This review discusses laser‐matter interaction mechanisms, laser surface engineering, and laser‐assisted fabrication of scaffolds and nanofibers.
Antonio Riveiro   +8 more
wiley   +1 more source

Adverse drug reactions related to methotrexate: a real-world pharmacovigilance study using the FAERS database from 2004 to 2024

open access: yesFrontiers in Immunology
ObjectiveTo comprehensively analyze the safety profile of Methotrexate in clinical use, clarify the incidence of adverse reactions and associated influencing factors, and provide evidence for safe medication practices in clinical settings.MethodsThis ...
Siyu Liu   +9 more
doaj   +1 more source

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