Results 131 to 140 of about 13,793,115 (299)

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Adverse drug reactions reporting at a referral hospital in Zimbabwe

, 2004
To establish factors influencing voluntary reporting of adverse drug reactions among health workers. A second objective was to establish the level of awareness on adverse drug reaction reporting and attitudes towards the voluntary adverse drug reaction ...
Khoza, S.
core   +2 more sources

Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin

Advanced Healthcare Materials, EarlyView.
Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi, Gülçin Arslan Azizoğlu, Mark R. Prausnitz   +2 more
wiley   +1 more source

Intervenciones educacionales para incrementar la farmacovigilancia en una unidad de salud de familia

Acta Médica Peruana, 2022
Ana Rita Ribeiro Barbosa, Filipa Fontes, Joana Nuno, Susana Fernandes, Dinis Brito   +4 more
doaj   +1 more source

Adverse drug reactions related to methotrexate: a real-world pharmacovigilance study using the FAERS database from 2004 to 2024

Frontiers in Immunology
ObjectiveTo comprehensively analyze the safety profile of Methotrexate in clinical use, clarify the incidence of adverse reactions and associated influencing factors, and provide evidence for safe medication practices in clinical settings.MethodsThis ...
Siyu Liu, Zhang Yuan, Shicong Rao, Wenxing Li, Taiwei Wu, Shuzhen Deng, Yongying Zhong, Jinyu Lin, Wei Guo, Shiwei Yuan   +9 more
doaj   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Pharmacovigilance and adverse drug reaction reporting: a perspective of community pharmacists and pharmacy technicians in Sana’a, Yemen

, 2017
Yaser Mohammed Al-Worafi,1,2 Yaman Walid Kassab,3 Wafa Mohammed Alseragi,4 Masaad Saeed Almutairi,5 Ali Ahmed,6 Long Chiau Ming,7 Ali Saleh Alkhoshaiban,8,9 Muhammad Abdul Hadi10 1Faculty of Pharmacy, University of Science and Technology, Sana’a ...
Alseragi WM, Al-Worafi YM, Ming LC, Alkhoshaiban AS, Ahmed A, Kassab YW, Almutairi MS, Hadi MA   +7 more
core  

Safety evaluation of selective estrogen receptor degraders (SERDs) using real-world evidence from the FDA Adverse Event Reporting System (FAERS)

Scientific Reports
This study aims to evaluate post-marketing adverse event data for two selective estrogen receptor degraders (SERDs) in a real-world context, identify potential risk signals, and offer insights for clinical pharmacovigilance.
Ye Kang, Xue Sun, Da-sheng Dang, Yuan Yuan   +3 more
doaj   +1 more source

Tumor‐Targeted Hyaluronic Acid/Tannic Acid‐Engineered Oxygen Nanogenerators With IR780 Payloads Enable Dual‐Mode Glutathione Depletion and Effective Singlet Oxygen Generation for Melanoma Treatment

Advanced Healthcare Materials, EarlyView.
A hyaluronic acid/tannic acid‐engineered Prussian blue oxygen nanogenerator loaded with IR780 is developed to enhance melanoma phototherapy. By integrating tumor targeting, oxygen self‐supply, and dual‐mode glutathione depletion, the nanoplatform effectively overcomes hypoxia and antioxidant defenses, potentiating synergistic photothermal/photodynamic ...
Chai‐How Hsu, I‐Ju Liu, Hsiang‐Yun Chih, Tsai‐Ching Hsu, Ju‐An Liang, Chia‐Wei Kuo, Bor‐Show Tzang, Wen‐Hsuan Chiang   +7 more
wiley   +1 more source

Spontaneous Adverse Drug Reaction Reporting Vs Event Monitoring: A Comparison

, 1991
Spontaneous adverse drug reaction (ADR) reporting is the mainstay of national and international drug safety evaluation in the post-approval phase. A major criticism of the method has been a high, but essentially unquantifiable, level of under-reporting ...
A P Fletcher
core   +1 more source