Results 161 to 170 of about 976,952 (369)

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

GASCADE: Grouped Summarization of Adverse Drug Event for Enhanced Cancer Pharmacovigilance [PDF]

open access: yesarXiv
In the realm of cancer treatment, summarizing adverse drug events (ADEs) reported by patients using prescribed drugs is crucial for enhancing pharmacovigilance practices and improving drug-related decision-making. While the volume and complexity of pharmacovigilance data have increased, existing research in this field has predominantly focused on ...
arxiv  

Investigating the Detection of Adverse Drug Events in a UK General Practice Electronic Health-Care Database [PDF]

open access: yesarXiv, 2013
Data-mining techniques have frequently been developed for Spontaneous reporting databases. These techniques aim to find adverse drug events accurately and efficiently. Spontaneous reporting databases are prone to missing information, under reporting and incorrect entries.
arxiv  

An Overview of Clinical Pharmacology of Ibuprofen

open access: yesOman Medical Journal, 2010
Ibuprofen was the first member of Propionic acid derivatives introduced in 1969. It is a popular domestic and over the counter analgesic and antipyretic for adults and children.
Nousheen Aslam, Rabia Bushra
doaj  

BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs

open access: yesBMC Bioinformatics, 2011
Background The identification of drug characteristics is a clinically important task, but it requires much expert knowledge and consumes substantial resources.
Tsafnat Guy   +4 more
doaj   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Research on Adverse Drug Reaction Prediction Model Combining Knowledge Graph Embedding and Deep Learning [PDF]

open access: yesarXiv
In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent prediction models need to be constructed for each adverse reaction of drugs, and the prediction accuracy is low, this ...
arxiv  

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