Results 91 to 100 of about 585,279 (298)

Adverse Drug Reaction Classification With Deep Neural Networks [PDF]

open access: yes, 2016
We study the problem of detecting sentences describing adverse drug reactions (ADRs) and frame the problem as binary classification. We investigate different neural network (NN) architectures for ADR classification.
He, Yulan   +3 more
core   +1 more source

Adverse drug reactions [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 2015
Rieder, Michael, Ferro, Albert
openaire   +3 more sources

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Cutaneous adverse reactions to monoclonal antibody treatments [PDF]

open access: yes, 2009
peer reviewedA number of adverse skin reactions can occur during some treatments using monoclonal antibodies. Some of the reactions are specifically linked to the pharmacological effect of the drug. Others are the expression of more common drug reactions.
Pierard, Claudine, Pierard, Gérald
core  

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti   +19 more
wiley   +1 more source

Proton-pump inhibitor use is associated with a broad spectrum of neurological adverse events including impaired hearing, vision, and memory. [PDF]

open access: yes, 2019
Proton-pump inhibitors, PPIs, are considered effective therapy for stomach acid suppression due to their irreversible inhibition of the hydrogen/potassium pump in the gastric parietal cells. They are widely prescribed and are considered safe for over-the-
Abagyan, Ruben   +4 more
core   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Pharmacogenomics and Adverse Drug Reactions in Children

open access: yesFrontiers in Genetics, 2014
Adverse drug reactions are a common and important complication of drug therapy in children. Over the past decade it has become increasingly apparent that genetically controlled variations in drug disposition and response are important determinants of ...
Michael John Rieder, Bruce eCarleton
doaj   +1 more source

A structural equation model of adverse events and length of stay in hospitals [PDF]

open access: yes
Adverse events in hospitals cause significant morbidity and mortality, and considerable effort has been invested into analysing their incidence and preventability. An unresolved issue in models of medical adverse events is potential endogeneity of length
Katharina Hauck, Xueyan Zhao
core  

Nursing and adverse drug reactions: a dawning role [PDF]

open access: yes, 2018
Trabajo fin de grado en EnfermeríaObjetivo: El presente trabajo pretende explorar y definir el rol de la enfermera en la detección y notificación de las reacciones adversas a medicamentos.
Garavito Acebes, Patricia
core  

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