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Voriconazole-associated adverse drug reactions in Chinese patients: incidence, clinical features and the predictive value of ALBI score for hepatotoxicity. [PDF]
Front PharmacolHu L, Su Y, Tang X, Li Y, Hou J.
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Medicina Clínica (English Edition), 2020
An adverse drug reaction (ADR) is defined as a response to a medicinal product which is noxious and unintended. ADRs are an important cause of morbidity and mortality and increase health costs. The pharmacovigilance systems allow the identification and prevention of the risks associated with use of a drug, especially of recently marketed drugs; they ...
Eva Montané, Javier Santesmases
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An adverse drug reaction (ADR) is defined as a response to a medicinal product which is noxious and unintended. ADRs are an important cause of morbidity and mortality and increase health costs. The pharmacovigilance systems allow the identification and prevention of the risks associated with use of a drug, especially of recently marketed drugs; they ...
Eva Montané, Javier Santesmases
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Postgraduate Medicine, 1965
The present trend toward polypharmacy increases the likelihood of adverse drug reactions and obscures the relationship of drugs to complications. Both host factors and drug factors predispose to the development of an adverse reaction. Reactions may be related to therapeutic or nontherapeutic effects of drugs. Other categories include allergic reactions
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The present trend toward polypharmacy increases the likelihood of adverse drug reactions and obscures the relationship of drugs to complications. Both host factors and drug factors predispose to the development of an adverse reaction. Reactions may be related to therapeutic or nontherapeutic effects of drugs. Other categories include allergic reactions
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Pharmacogenetics and Adverse Drug Reactions
Lancet, The, 2000Polymorphisms in the genes that code for drug-metabolising enzymes, drug transporters, drug receptors, and ion channels can affect an individual's risk of having an adverse drug reaction, or can alter the efficacy of drug treatment in that individual.
Urs A Meyer
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British Medical Bulletin, 1990
The elderly have benefitted considerably from the vast increase in the range of drugs available for prescription. However it is now well recognized that the incidence in adverse drug reactions increases with age. This is mainly due to altered pharmacodynamics and pharmacokinetics as well as multiple prescribing and the effect of illness rather than the
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The elderly have benefitted considerably from the vast increase in the range of drugs available for prescription. However it is now well recognized that the incidence in adverse drug reactions increases with age. This is mainly due to altered pharmacodynamics and pharmacokinetics as well as multiple prescribing and the effect of illness rather than the
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Adverse Drug Reactions and the Elderly
Health Affairs, 1990Virtually all medications can produce undesirable side effects. The elderly are more likely to experience these adverse reactions as the result of age-related increases in the frequency of drug use, sensitivity to drug effects, and prevalence of predisposing conditions that can increase the frequency and severity of adverse drug reactions.
W A, Ray, M R, Griffin, R I, Shorr
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Adverse Drug Reactions in Neonates
The Journal of Clinical Pharmacology, 1994Adverse drug reactions (ADR) are uncommon causes of admission of neonates to the neonatal intensive care unit. The neonate, however, is potentially at significant risk for adverse drug reactions because of underdeveloped mechanisms and systems for handling drugs (the Gray Baby Syndrome with chloramphenicol as a classic example), the fact that infants ...
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