Results 31 to 40 of about 585,279 (298)

Reporting of adverse drug reactions in randomised controlled trials – a systematic survey [PDF]

open access: yes, 2001
BACKGROUND: Decisions on treatment are guided, not only by the potential for benefit, but also by the nature and severity of adverse drug reactions. However, some researchers have found numerous deficiencies in trial reports of adverse effects. We sought
Sheena Derry, Yoon Kong Loke
core   +2 more sources

Severe adverse drug reactions [PDF]

open access: yesClinical Medicine, 2016
Severe cutaneous adverse reactions (SCARs) can present in a multitude of ways including Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, and acute generalised exanthematous pustulosis. While the prognosis and therapy for these conditions may vary, it is crucial that the culprit drug is ...
Ying Xin, Teo, Sarah Anne, Walsh
openaire   +2 more sources

Trilostane in dogs [PDF]

open access: yes, 2010
Over the last 10 years, trilostane, a competitive inhibitor of steroid synthesis, is being widely used for the treatment of canine hyperadrenocorticism.
Alenza   +59 more
core   +1 more source

Pharmacovigilance of Severe Cutaneous Adverse Drug Reactions

open access: yesClinical Dermatology Review, 2022
Background: Severe cutaneous adverse drug reactions (SCARs) are idiosyncratic reactions comprising 2% of all drug-induced skin reactions. These include Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis, drug reaction with eosinophilia and ...
Kriteeka Saini, Amita Sutaria, Bela Shah
doaj   +1 more source

Children and ADRs (Adverse Drug Reactions)

open access: yesItalian Journal of Pediatrics, 2010
Many medicines are prescribed to the paediatric population on an unlicensed or 'off-label' basis because they have not been adequately tested and/or formulated and authorized for use in appropriate paediatric age groups.
Napoleone Ettore
doaj   +1 more source

Age-Associated Risk of Liver-Related Adverse Drug Reactions

open access: yesFrontiers in Medicine, 2022
ObjectiveAging population is generally considered more sensitive to adverse drug reactions (ADRs). Yet, big data-based quantitative evidence currently does not exist to support this concept.
Yan-zhong Han   +12 more
doaj   +1 more source

Bayesian model selection in logistic regression for the detection of adverse drug reactions [PDF]

open access: yes, 2015
Motivation: Spontaneous adverse event reports have a high potential for detecting adverse drug reactions. However, due to their dimension, exploring such databases requires statistical methods.
Marbac, Matthieu   +2 more
core   +3 more sources

Dermoscopic Aspects of Cutaneous Adverse Drug Reactions

open access: yesDermatology Practical & Conceptual, 2021
Background: Little is known about the dermoscopic evaluation of cutaneous adverse drug reactions (CADRs). Objectives: To evaluate the dermoscopic patterns of CADRs and identify those associated with severe cutaneous adverse reactions to drugs (SCARDs).
Gabriela Rossi   +2 more
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Adverse drug reactions in self-medication [PDF]

open access: yesСаратовский научно-медицинский журнал, 2012
The research goal is to study the actual problem of self-medication. The Association of the European Self-Medication Industry (AESGP) considers the term «responsible self-medication».
Smuseva O.N., Solovkina Yu.V.
doaj  

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