Results 31 to 40 of about 302,876 (262)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
HLA‐associated adverse drug reactions ‐ scoping review
Clinical and Translational Science, 2021 Alleles of the human leukocyte antigen (HLA) system have been associated with the occurrence of idiosyncratic adverse drug reactions (ADRs). Accordingly, it is assumed that pre‐emptive testing for the presence of certain HLA alleles (HLA‐typing) could ...
Chiara Jeiziner +4 more
doaj +1 more source
A prospective observational study of ophthalmic adverse drug reactions in a tertiary care hospital
National Journal of Physiology, Pharmacy and Pharmacology, 2021 Background: According to an epidemiological study, 1.725.1% of eye disease was drug induced, but the evidence of adverse drug reactions (ADRs) in ophthalmology is found to be scarce, as it is difficult in correlation between symptoms and ocular signs ...
Vasundara Krishnaiah +2 more
doaj +1 more source
BMJ, 1998 An adverse reaction to a drug has been defined as any noxious or unintended reaction to a drug that is administered in standard doses by the proper route for the purpose of prophylaxis, diagnosis, or treatment. Some drug reactions may occur in everyone, whereas others occur only in susceptible patients.
D, Vervloet, S, Durham
openaire +3 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Frontiers in PharmacologyBackgroundPharmacologic agents with proposed neuroprotective properties are increasingly investigated; however, limited regulation and heterogeneous evidence raise concerns about their safety profiles. To establish a foundation for its safe clinical use,
Yu-yao Guan +4 more
doaj +1 more source
Adverse drug reactions in self-medication [PDF]
Саратовский научно-медицинский журнал, 2012 The research goal is to study the actual problem of self-medication. The Association of the European Self-Medication Industry (AESGP) considers the term «responsible self-medication».
Smuseva O.N., Solovkina Yu.V.
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Spontaneous notification of adverse drug reactions
Revista Cubana de Medicina Militar, 2021 Introduction: The proper use of medications eliminates or controls numerous diseases, contributes to the well-being of the population and increases life expectancy; but it can also generate adverse reactions, which must be reported to identify new risks ...
Laura Barrero Viera +1 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source