Results 71 to 80 of about 11,663,292 (306)

Tolerability of Ramipril 10 mg Daily in High-risk Cardiovascular Patients in Taiwan: Experience from Kaohsiung Medical University Chung-Ho Memorial Hospital

open access: yesKaohsiung Journal of Medical Sciences, 2005
The Heart Outcomes Prevention Evaluation (HOPE) study demonstrated that the angiotensin-converting enzyme inhibitor, ramipril, significantly reduces mortality, myocardial infarction and stroke in high-risk cardiovascular patients, beyond the benefits ...
Chih-Sheng Chu   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Adverse Selection in the Annuity Market with Sequential and Simultaneous Insurance Demand [PDF]

open access: yes
This paper investigates the effect of adverse selection on the private annuity market in a model with two periods of retirement. In order to introduce the existence of limited-time pension insurance, we assume that for each period of retirement separate ...
Johann K. Brunner, Susanne Pech
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Why Adverse Selection Need Not Be Adverse [PDF]

open access: yes, 2015
Restrictions on insurance risk classification can lead to troublesome adverse selection. A simple version of the usual argument is as follows. If insurers cannot charge risk-differentiated premiums, more insurance is bought by higher risks and less ...
Tapadar, Pradip
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Adverse Reactions of COVID-19 Vaccines: A Scoping Review of Observational Studies

open access: yesInternational Journal of General Medicine, 2023
Inge Dhamanti,1– 3 Auliya A Suwantika,4– 6 Amirah Adlia,7 Laura Navika Yamani,8,9 Fitri Yakub10 1Department of Health Policy and Administration, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia; 2Center for Patient Safety Research ...
Dhamanti I   +4 more
doaj  

Adverse Effects of Telemedicine

open access: yesAnnals of Indian Academy of Neurology, 2022
Sookaromdee, Pathums, Wiwanitkit, Viroj
openaire   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Health care resource use and costs associated with possible side effects of high oral corticosteroid use in asthma: a claims-based analysis

open access: yesClinicoEconomics and Outcomes Research, 2016
Allan T Luskin,1 Evgeniya N Antonova,2 Michael S Broder,3 Eunice Y Chang,3 Theodore A Omachi,2 Dennis K Ledford4 1HealthyAirways, Madison, WI, 2Genentech, Inc., South San Francisco, 3Partnership for Health Analytic Research, LLC, Beverly Hills, CA ...
Luskin AT   +5 more
doaj  

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