Results 91 to 100 of about 15,484,713 (310)
ADVERSE EFFECTS OF ANTIEPILEPTIC DRUGS
Эпилепсия и пароксизмальные состояния, 2017 Antiepileptic drugs are frequently associated with a risk of adverse effects, which have an impact on the tolerability and success of treatment. Patients who develop intolerable adverse effects have to discontinue treatment early after initiation or to ...
I. Yu. Kovaleva
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Isotretinoin and the Kidney: Opportunities and Threats
Clinical, Cosmetic and Investigational Dermatology, 2020 Bahareh Forouzani-Haghighi, Iman Karimzadeh Department of Clinical Pharmacy, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, IranCorrespondence: Iman KarimzadehDepartment of Clinical Pharmacy, Faculty of Pharmacy, Shiraz University of
Forouzani-Haghighi B, Karimzadeh I
doaj
Disulfiram-induced psychosis at a therapeutic dose and in clear sensorium: Two case demonstrations
Journal of Mental Health and Human Behaviour, 2019 The literature on disulfiram induced psychosis showed, it was either associated with delirium or preceded by a prescription of a higher dose. We report two cases of psychosis in clear sensorium developing in individuals with alcohol dependence without ...
Abhishek Ghosh +3 more
doaj +1 more source
Frontiers in Pharmacology, 2018 RTJ receives salary support from the Peter Brojde Lung Cancer Centre and the Backler Foundation, Jewish General Hospital Foundation.
K. Nurgali +3 more
semanticscholar +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Double guide catheter technique for sealing an iatrogenic coronary perforation
Research in Cardiovascular Medicine, 2016 Introduction: Coronary vessel perforation is one of the most feared complications of coronary angioplasty. The treatment of this complication relies mostly on the implantation of covered stents.
Miguel Rodriguez-Santamarta +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Common and less common adverse effects of antihypertensives: a general practitioner’s perspective
South African Family Practice, 2012 No abstract available.
Y. Trinder
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source