Results 41 to 50 of about 11,499,753 (260)

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Enhancing Communication about Paediatric Medicines: Lessons from a Qualitative Study of Parents' Experiences of Their Child's Suspected Adverse Drug Reaction [PDF]

, 2012
Background: There is little research on parents' experiences of suspected adverse drug reactions in their children and hence little evidence to guide clinicians when communicating with families about problems associated with medicines.
Smyth, RL, Young, B., Hesselgreaves, H, Munir Pirmohamed (40546), Janine Arnott (128747), Turner, M.A., Anthony J Nunn, Rosalind L. Smyth (80205), Mark A. Turner (114089), Hesselgreaves Hannah, Nunn, Anthony J., Nunn Anthony J., Nunn, Anthony J, Turner, Mark A, Matthew Peak (114087), Hesselgreaves, H., Pirmohamed, Munir, Nunn, AJ, Pirmohamed, M, Peak, M, Munir Pirmohamed, Smyth Rosalind L., Janine Arnott, Arnott Janine, Pirmohamed Munir, Nunn, A.J., Hannah Hesselgreaves (128748), Peak, M., Bridget Young (128749), Hannah Hesselgreaves, Bridget Young, Anthony J. Nunn (114088), Young, Bridget, Matthew Peak, Arnott, J, Turner Mark A., Turner, MA, Young, B, Rosalind L Smyth, Pirmohamed, M., Smyth, Rosalind L., Hesselgreaves, Hannah, Mark A Turner, Smyth, Rosalind L, Arnott, Janine, Young Bridget, Peak Matthew, Arnott, J., Smyth, R.L., Peak, Matthew, Turner, Mark A.   +50 more
core   +1 more source

Association between Silicone Breast Implants and Autoimmune Diseases

Gazeta Médica, 2017
BACKGROUND AND AIM: Silicone breast implants have, for a long time, been considered as biologically inert and harmless. However the relationship between silicone breast implants and the risk of autoimmune diseases has generated intense medical interest ...
Rute Carvalho, Ana Filipa S. Lima, Joana Barreira, Vânia Guedes   +3 more
doaj   +2 more sources

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Green rush and red warnings: Retrospective chart review of adverse events of interactions between cannabinoids and psychotropic drugs

Frontiers in Pharmacology
AimOur objective was to systematically assess the prevalence and clinical features of adverse events related to interactions between cannabinoids and psychotropic drugs through a retrospective chart review.Methodology1586 adverse event reports were ...
Adrian Andrzej Chrobak, Jarosław Woroń, Jarosław Woroń, Jarosław Woroń, Marcin Siwek   +4 more
doaj   +1 more source

OXICOLOGICAL AND PATHOLOGICAL STUDIES ON THE ADVERSE EFFECTS OF INSECTICIDE TRICHLORFON (METRIFONATE) IN ALBINO RATS WITH SPECIAL REFERENCE TO MALE FERTILITY [PDF]

Kafrelsheikh Veterinary Medical Journal, 2010
The present investigation was carried out to study the adverse effects of organophosphorus insecticide trichlorfon by both therapeutic and toxic doses on albino rats with special reference to male fertility through recording the changes in serum ...
Gihan Moustafa, Zeinab, M. Labib, Naglaa, Z. H. Eleiwa   +2 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Adverse side-effects to biological agents

, 2006
Biological agents-like cytokines, monoclonal antibodies and fusion proteins are widely used in anti-inflammatory and tumour therapy. They are highly efficient in certain diseases, but can cause a great variety of adverse side-effects.
Pichler, W J
core   +1 more source

Allergy to penicillin and betalactam antibiotics

Einstein (São Paulo)
Betalactams are the most frequent cause of hypersensitivity reactions to drugs mediated by a specific immune mechanism. Immediate reactions occur within 1 to 6 hours after betalactam administration, and are generally IgE-mediated.
Mara Morelo Rocha Felix, Marcelo Vivolo Aun, Ullissis Pádua de Menezes, Gladys Reis e Silva de Queiroz, Adriana Teixeira Rodrigues, Ana Carolina D’Onofrio-Silva, Maria Inês Perelló, Inês Cristina Camelo-Nunes, Maria Fernanda Malaman   +8 more
doaj   +2 more sources