Results 101 to 110 of about 1,406,780 (315)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Personal Bankruptcy: Reconciling Adverse Events and Strategic Timing Hypotheses Using Heterogeneity in Filing Types [PDF]

The strategic timing and adverse events hypotheses of personal bankruptcy have received particular attention. Existing research focuses on proving or disproving either hypothesis, using a strict interpretation of the role of financial benefit in the ...
Tarun Sabarwal, Shuoxun Zhang, Li Gan
core  

Written reports of adverse events in acute care—A discourse analysis

, 2019
Adverse health care events are a global public health issue despite major efforts, and they have been acknowledged as a complex concern. The aim of this study was to explore the construction of unsafe care using accounts of adverse events concerning the ...
Wijk, Helle,, Ulin, Kerstin,, Helle Wijk, Gyberg, Anna, Margret Lepp, Anna Gyberg, Ingela Henoch, Henoch, Ingela,, Ulin, Kerstin, Kerstin Ulin, Gyberg, Anna,, Lepp, Margret, Lepp, Margret,, Wijk, Helle, Henoch, Ingela   +14 more
core   +1 more source

Efficacy, retention, and safety of baricitinib in real-life: HUR-BIO monocentric experience

Ulusal Romatoloji Dergisi
Objective: This study evaluates the effectiveness, retention rate and safety of baricitinib, including a comparison between baricitinib and a tumour necrosis factor inhibitor (adalimumab) in a real-life cohort of patients with rheumatoid arthritis (RA).
Mustafa Ekici, İrem Yıldız İçli, Ece Ersal Deregözü, Emre Bilgin, Zehra Özsoy, Gizem Ayan, Gül Sandal Uzun, Erdinç Ünaldı, Büşra Fırlatan Yazgan, Gözde Sevgi Kart Bayram, Buğu Bulat, Levent Kılıç, Ali Akdoğan, Şule A. Bilgen, Sedat Kiraz, İhsan Ertenli   +15 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Implementing a 48 h EWTD-compliant rota for junior doctors in the UK does not compromise patients’ safety : assessor-blind pilot comparison [PDF]

, 2009
Background: There are currently no field data about the effect of implementing European Working Time Directive (EWTD)-compliant rotas in a medical setting.
Bennett-Jones, David, Lowe, Alice, Taggart, Frances M., Sullivan, J.P., Landrigan, C. P., Pounder, R., Cappuccio, Francesco, Kamdala, N B, Lockley, S. W., Taggart, Frances, Cooper, Dan, Landrigan, Christopher, Czeisler, Charles, Miller, Marianne, Edmunds, Mair, Bakewell, A., Lockley, Steven, Ward, Gregory, Chen, Ji, Pohl, Joseph, Kidd, Jane, Peile, Ed, Sullivan, Jason, Ward, G., Edmunds, M., Bakewell, Anne, Pounder, Roy, Ji, Chen, Short, Alasdair   +28 more
core   +1 more source

Comparison of immune checkpoint inhibitors related to pulmonary adverse events: a retrospective analysis of clinical studies and network meta-analysis

BMC Medicine
Background Immune checkpoint inhibitors (ICIs) have transformed tumor treatment. However, the risk of pulmonary adverse events (PAEs) associated with ICI combination therapy is still unclear.
Baohui Hong, Bin Du, Rong Chen, Caiyun Zheng, Ruping Ni, Maobai Liu, Jing Yang   +6 more
doaj   +1 more source

Association of community distress and risk of adverse events on the lung transplant waitlist

JHLT Open
Background: Socioeconomic disparities in lung transplantation outcomes have been well described, but little is known about the impact of community-level disparities amongst waitlisted patients. This study examines the relationship between community-level
Alan M. Jacob, MS, William Brandon, MD, Colin Dunn, MD, Song Zhang, PhD, Ang Gao, MS, Fernando Torres, MD, Adrian C. Lawrence, MD, Irina L. Timofte, MD, Srinivas Bollineni, MD, Manish R. Mohanka, MD, Juan Deleija-Lujano, MD, Adnan Khan, MD, Joseph Crossno, MD, Michael Wait, MD, Matthias Peltz, MD, Christopher A. Heid, MD, Lynn Huffman, MD, Steve Ring, MD, John Murala, MD, Suresh Keshavamurthy, MD, Jaye Weston, MD, Vaidehi Kaza, MD   +21 more
doaj   +1 more source

Immunisation adverse events clinics [PDF]

New South Wales Public Health Bulletin, 2003
As the incidence of vaccine preventable diseases has declined, and more new vaccines are marketed, adverse events following immunisation have attracted greater attention from the public and from health care providers. At a population level, post-licensure monitoring of vaccine safety in many countries relies on notifications to passive surveillance ...
openaire   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source