Results 1 to 10 of about 913,703 (307)

Serious Neurological Adverse Events of Ceftriaxone [PDF]

Antibiotics, 2021
We described ceftriaxone-induced CNS adverse events through the largest case series of Adverse Drug Reactions (ADRs) reports, from 1995 to 2017, using the French Pharmacovigilance Database.
Clémence Lacroix, Annie-Pierre Bera-Jonville, François Montastruc, Lionel Velly, Joëlle Micallef, Romain Guilhaumou   +5 more
doaj   +4 more sources

Serious adverse events and fatal adverse events associated with nivolumab treatment in cancer patients [PDF]

Journal for ImmunoTherapy of Cancer, 2018
Background Nivolumab, an immune checkpoint inhibitor, has revolutionized the treatment of many cancers. Due to its novel mechanisms of action, nivolumab induces a distinct profile of adverse events. Currently, the incidence and risk of developing serious
Bin Zhao, Hong Zhao, Jiaxin Zhao
doaj   +3 more sources

Analysis of Reporting Trends of Serious Adverse Events Associated With Anti‐Obesity Drugs [PDF]

Pharmacology Research & Perspectives
Concern over the side effects of anti‐obesity medications, particularly if severe, has grown as their use has increased. Thus, the objective was to use trends in the reporting of suspected adverse events associated with anti‐obesity medications that have
Branislava B. Raičević, Andrej Belančić, Nikola Mirković, Slobodan M. Janković   +3 more
doaj   +2 more sources

Postmarketing Surveillance of Full Spectrum Hemp Extract CBD Products: Reported Adverse Events and Serious Adverse Events [PDF]

Drugs - Real World Outcomes
Background There is a growing interest in products featuring hemp extracts and a demand for more data regarding their safety. To date, there is a paucity of published data on the safety of these products. Methods A retrospective analysis of postmarketing
Colleen M. Kingsbury, Ivori Zvorsky, Kevin Spelman   +2 more
doaj   +2 more sources

Insights into pathologic mechanisms occurring during serious adverse events following live zoster vaccination [PDF]

Journal of Virology
An effective live zoster vaccine has been widely used around the world. Although no deaths occurred in the original large clinical trial, we analyzed 10 serious adverse events, including six deaths that have subsequently occurred in four countries.
Peter G. E. Kennedy, Charles Grose
doaj   +2 more sources

Adverse Events of DOACs in Children

Frontiers in Pediatrics, 2022
Venous thromboembolism (VTE) has an increasing rate of significance in pediatric patients. The currently standardized anticoagulants (unfractionated heparin, low molecular weight heparin and vitamin K antagonists) and their dose regimens were not ...
Alessandra Bosch, Manuela Albisetti, Manuela Albisetti   +2 more
doaj   +1 more source

Overlap between adverse events (AEs) and serious adverse events (SAEs): a case study of a phase III cancer clinical trial

Trials, 2020
Background Safety data is required to be collected in all clinical trials and can be separated into two types of data, adverse events and serious adverse events.
Elizabeth C. James, David Dunn, Adrian D. Cook, Andrew R. Clamp, Matthew R. Sydes   +4 more
doaj   +1 more source

A systematic review and meta-analysis of the safety of anti-interleukin therapy in COVID-19 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2022
Objective. To evaluate safety of anti-interleukin drugs used as a pathogenetic therapy of COVID-19 as assessed by risks of infectious complications. Materials and Methods.
Gomon Yu.M., Kolbin A.S., Strizheletsky V.V., Ivanov I.G., Sultanova F.M., Balykina Yu.E.   +5 more
doaj   +1 more source

Risk Factors and Incidence Rates of Self-Reported Short-Term Adverse Events of COVID-19 Vaccine Booster Dose

Vaccines, 2022
With the spread of the new SARS-CoV-2 variants, many countries have begun COVID-19 vaccine booster programs with the mix-and-match strategy. However, research on the adverse events (AE) of booster doses is still scarce.
Po-Yu Chen, Bih-Ju Wu, Mei-Chin Su, Yen-Hsi Lin, Shu-Chiung Chiang, Jau-Ching Wu, Tzeng-Ji Chen, Yu-Chun Chen   +7 more
doaj   +1 more source

Safety monitoring of COVID-19 vaccination among adolescents aged 12 to 17 years old in the Republic of Korea [PDF]

Osong Public Health and Research Perspectives, 2022
Objectives This study aimed to disseminate information on coronavirus disease 2019 (COVID-19) vaccine safety among adolescents aged 12 to 17 years in the Republic of Korea.
Seontae Kim, Insob Hwang, Mijeong Ko, Yunhyung Kwon, Yeon-Kyeng Lee   +4 more
doaj   +1 more source