Clinical Trial Readiness in Limb Girdle Muscular Dystrophy R1 (LGMDR1): A GRASP Consortium Study
ABSTRACT Objective Identifying functional measures that are both valid and reliable in the limb girdle muscular dystrophy (LGMD) population is critical for quantifying the level of functional impairment related to disease progression in order to establish clinical trial readiness in the context of anticipated therapeutic trials.
Stephanie M. Hunn+29 more
wiley +1 more source
ABSTRACT Objective To investigate the reliability of very high‐frequency oscillations (VHFOs, 500–2000 Hz) as biomarkers in identifying the epileptogenic zone (EZ) in mesial temporal lobe epilepsy (MTLE) patients. Methods We reviewed 19 MTLE patients who underwent stereo‐electroencephalography‐guided radiofrequency thermocoagulation.
Stéphane Jean+10 more
wiley +1 more source
Review: acellular vaccines prevent pertussis as effectively as whole-cell vaccines with fewer adverse events [PDF]
Jim Buttery
openalex +1 more source
ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib+16 more
wiley +1 more source
Cardiac MRI study of adverse events in patients treated with immune checkpoint inhibitors: a prospective cohort study of cardiac adverse events. [PDF]
Losurdo A+22 more
europepmc +1 more source
Turning information into knowledge to prevent health care–associated infections and other adverse events: The electronic ICP as an agent of change [PDF]
Russell N. Olmsted
openalex +1 more source
ABSTRACT This study assessed whether continued treatment with anti‐CGRP monoclonal antibodies (mAbs) is driven more by reductions in monthly migraine days (MMDs) or patients' global impression of change (PGIC), a patient‐reported outcome. Among 169 patients treated with anti‐CGRP mAbs, 21.3% discontinued due to ineffectiveness. PGIC responders (≥ 5) at
Marina Romozzi+4 more
wiley +1 more source
Comparison of Laparoscopic and Robotic Intraoperative Adverse Events in Benign Gynecological Procedures and the Correlation of the Adverse Events With Postoperative Outcomes and Risk Analysis. [PDF]
Sinha R, Rupa B, Raina R, Bag M.
europepmc +1 more source
Intravascular ultrasound predictors of major adverse cardiac events in patients with unstable angina
Mariann Gyöngyösi+6 more
openalex +1 more source