Results 41 to 50 of about 1,406,780 (315)

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events

, 2010
Background An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in comparison with placebo in previous Cochrane reviews.
Christopher J Cates, Lasserson, TJ, Toby J Lasserson, Cates, CJ   +3 more
core   +1 more source

The Rise of Patient Safety-II: Should We Give Up Hope on Safety-I and Extracting Value From Patient Safety Incidents?; Comment on “False Dawns and New Horizons in Patient Safety Research and Practice” [PDF]

International Journal of Health Policy and Management, 2018
Who could disagree with the seemingly common-sense reasoning that: “We must learn from the things that go wrong.”? Despite major investments to improve patient safety, relatively few evaluations demonstrate convincing reductions in risk, harm, serious ...
Andrew Carson-Stevens, Liam Donaldson, Aziz Sheikh   +2 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998-2005. [PDF]

, 2007
BACKGROUND: Adverse drug reactions (ADRs) are a frequent cause of mortality and morbidity to patients worldwide, with great associated costs to the healthcare providers including the NHS in England.
Majeed, Azeem, Patel, M, Car, J, Molokhia, Mariam, Mariam Molokhia, Janakan Srishanmuganathan, Patel, H, Bell, Derek, Car, Josip; id_orcid, Srishanmuganathan, Janakan, Car, Josip, Majeed, A, Mitesh Patel, Patel, Hitesh, Josip Car, Bell, D, Molokhia, M, Patel, Mitesh, Derek Bell, Srishanmuganathan, J, Hitesh Patel, Azeem Majeed   +21 more
core   +1 more source

Cutaneous adverse events to systemic antineoplastic therapies: a retrospective study in a public oncologic hospital

Anais Brasileiros de Dermatologia, 2022
Background: Mucocutaneous adverse events are common during anticancer treatment, with variable consequences for the patient and their therapeutic regimen.
William Queiroz Guimarães Wiegandt Ceglio, Marina Mattos Rebeis, Marcela Ferreira Santana, Denis Miyashiro, Jade Cury-Martins, José Antônio Sanches   +5 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Neurodevelopmental outcomes after prenatal exposure to lamotrigine monotherapy in women with epilepsy: a systematic review and meta-analysis

BMC Pregnancy and Childbirth
Background Lamotrigine has become one of the most commonly prescribed antiseizure medications (ASM) in epileptic women during pregnancy and therefore requires regular updates regarding its safety.
Audrey Peron, Cyndie Picot, Lucie Jurek, Mikaïl Nourredine, Emmanuelle Ripoche, Priscilla Ajiji, Michel Cucherat, Judith Cottin   +7 more
doaj   +1 more source

Treatment Related Adverse Events in Children with Attention-Deficit / Hyperactivity Disorder Using Atomoxetine

Psychiatry and Behavioral Sciences, 2021
Objective: The aim of our study is to evaluate treatment related adverse events in children with attention-deficit/ hyperactivity disorder (ADHD) using atomoxetine.
Nurdan Kasar, Cigdem Yektas, Ali Evren Tufan   +2 more
doaj   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Pharmacovigilance in Vaccines: Importance, Main Aspects, Perspectives, and Challenges—A Narrative Review

Pharmaceuticals
Pharmacovigilance plays a central role in safeguarding public health by continuously monitoring the safety of vaccines, being critical in a climate of vaccine hesitancy, where public trust is paramount.
Katharine Valéria Saraiva Hodel, Bianca Sampaio Dotto Fiuza, Rodrigo Souza Conceição, Augusto Cezar Magalhães Aleluia, Thassila Nogueira Pitanga, Larissa Moraes dos Santos Fonseca, Camila Oliveira Valente, Cintia Silva Minafra-Rezende, Bruna Aparecida Souza Machado   +8 more
doaj   +1 more source