Results 71 to 80 of about 4,636,278 (309)
Protocol for evaluation of the cost-effectiveness of ePrescribing systems and candidate prototype for other related health information technologies [PDF]
Background: This protocol concerns the assessment of cost-effectiveness of hospital health information technology (HIT) in four hospitals. Two of these hospitals are acquiring ePrescribing systems incorporating extensive decision support, while the other
Coleman, Jamie J. +26 more
core +2 more sources
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Background:Limited data exist regarding the incidence rate and hazard ratios (HRs) of major adverse cardiovascular events and mortality in the successful-delivery women with or without systemic lupus erythematosus.Methods:A retrospective, population ...
Wu, Lung-Sheng;Tang, Chao-Hsiun;Lin, Yu-Sheng;Lin, Chia-Pin;Hung, Sheng-Tzu;Hwa, Hsiao-Lin;Luo, Shue-Fen;Chu, Pao-Hsien +1 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Critical Overview on the Benefits and Harms of Aspirin
Aspirin is widely used internationally for a variety of indications, with the most prominent one being that of cardiovascular disease. However, aspirin has also been proposed as a treatment option in a diverse range of conditions such as diabetes ...
Chun Shing Kwok, Yoon K. Loke
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Hui Chen,1,2 Jiawei Liu,1,2 Mengmeng Zhang1,2 1Central Sterile Supply Department, West China Hospital Sichuan University, Chengdu, Sichuan, People’s Republic of China; 2School of Nursing, Sichuan University, Chengdu, Sichuan, People’s Republic of ...
Liu J, Zhang M, Chen H
core
Is fasting safe? A chart review of adverse events during medically supervised, water-only fasting
Background Evidence suggests that fasting, during which only water is consumed, results in potentially health promoting physiological effects. However, peer-reviewed research assessing the safety of water-only fasting is lacking.
John S. Finnell +3 more
doaj +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source

