Results 71 to 80 of about 4,636,278 (309)

Protocol for evaluation of the cost-effectiveness of ePrescribing systems and candidate prototype for other related health information technologies [PDF]

open access: yes, 2014
Background: This protocol concerns the assessment of cost-effectiveness of hospital health information technology (HIT) in four hospitals. Two of these hospitals are acquiring ePrescribing systems incorporating extensive decision support, while the other
Coleman, Jamie J.   +26 more
core   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Major Adverse Cardiovascular Events and Mortality in Systemic Lupus Erythematosus Patients After Successful Delivery: A Population-based Study

open access: yes, 2017
Background:Limited data exist regarding the incidence rate and hazard ratios (HRs) of major adverse cardiovascular events and mortality in the successful-delivery women with or without systemic lupus erythematosus.Methods:A retrospective, population ...
Wu, Lung-Sheng;Tang, Chao-Hsiun;Lin, Yu-Sheng;Lin, Chia-Pin;Hung, Sheng-Tzu;Hwa, Hsiao-Lin;Luo, Shue-Fen;Chu, Pao-Hsien   +1 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Adverse events [PDF]

open access: yesAmerican Journal of Orthodontics and Dentofacial Orthopedics, 2017
  +5 more sources

Critical Overview on the Benefits and Harms of Aspirin

open access: yesPharmaceuticals, 2010
Aspirin is widely used internationally for a variety of indications, with the most prominent one being that of cardiovascular disease. However, aspirin has also been proposed as a treatment option in a diverse range of conditions such as diabetes ...
Chun Shing Kwok, Yoon K. Loke
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Incidence of Adverse Events in Central Sterile Supply Department: A Single-Center Retrospective Study

open access: yes, 2023
Hui Chen,1,2 Jiawei Liu,1,2 Mengmeng Zhang1,2 1Central Sterile Supply Department, West China Hospital Sichuan University, Chengdu, Sichuan, People’s Republic of China; 2School of Nursing, Sichuan University, Chengdu, Sichuan, People’s Republic of ...
Liu J, Zhang M, Chen H
core  

Is fasting safe? A chart review of adverse events during medically supervised, water-only fasting

open access: yesBMC Complementary and Alternative Medicine, 2018
Background Evidence suggests that fasting, during which only water is consumed, results in potentially health promoting physiological effects. However, peer-reviewed research assessing the safety of water-only fasting is lacking.
John S. Finnell   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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