Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae +5 more
wiley +1 more source
Immunological Role of the Maternal Uterine Microbiota in Postpartum Hemorrhage
Recent metagenomics and microbiology studies have identified microorganisms that are typical of the fetoplacental unit. Considering this emerging evidence, the placenta, uterus, and the amniotic cavity are not sterile and not immune privileged.
Maria F. Escobar +3 more
doaj +1 more source
Preconception care for diabetic women for improving maternal and fetal outcomes : a systematic review and meta-analysis [PDF]
Background Preexisting diabetes mellitus is associated with increased risk for maternal and fetal adverse outcomes. Despite improvement in the access and quality of antenatal care recent population based studies demonstrating increased congenital ...
Ghada A Bawazeer +11 more
core +1 more source
m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang +18 more
wiley +1 more source
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao +15 more
wiley +1 more source
Background In nonpregnant populations, obesity staging systems such as the Edmonton Obesity Staging System (EOSS) improve risk stratification of patients with obesity by also accounting for medical comorbidities.
Sarah E. White, David M. Stamilio
doaj +1 more source
The Relation between Treated Maternal Urinary Tract Infection and Adverse Maternal, Prenatal Outcomes in Pregnant Women of Ardabil, Iran [PDF]
Background and Objective: Urinary tract infection is one of the most common bacterial infections during pregnancy and has also been implicated as a risk factor for adverse maternal and prenatal outcomes.
مرادی, شهلا +5 more
core
The effect of overweight and obesity on fecundity and pregnancy outcome amongst women in sub-Saharan Africa [PDF]
Background: Obesity is an emerging public health concern in Sub-Saharan Africa and adult women are the population group most likely to be obese. Previous research conducted in high-income countries has demonstrated that high body mass index (BMI) has ...
Cresswell, Jennifer Anne
core +1 more source
An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer +12 more
wiley +1 more source
Prediction of adverse maternal outcomes associated with preeclampsia in twin pregnancies
Background We aimed to investigate risk factors of adverse maternal outcomes associated with preeclampsia (PE) in twin pregnancies and develop a simplified clinical prediction model.
Shuisen Zheng +5 more
doaj +1 more source

