Results 201 to 210 of about 436,508 (289)

Retrospective analysis of adverse pregnancy outcomes associated with hepatitis B virus infection. [PDF]

BMC Pregnancy Childbirth
Cong J, Guo Y, Yi W.
europepmc   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Addressing maternal cardiovascular risk: The impact of lactation, adverse pregnancy outcomes, and racial disparities. [PDF]

Am Heart J Plus
Rodriguez M, McCarroll ML, Marrs C, Tamirisa KP.   +3 more
europepmc   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Prognostic Value of Lupus Anticoagulant and Anti-β2 Glycoprotein I Antibody in Adverse Pregnancy Outcomes. [PDF]

Arthritis Rheumatol
Nonobe M, Otani T, Yoshihara H, Goto S, Kitaori T, Nishikawa N, Fujieda Y, Atsumi T, Sugiura-Ogasawara M.   +8 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Prevalence of Gestational Diabetes Mellitus and associations with adverse pregnancy outcomes in the Faroe Islands: a population-based study. [PDF]

BMC Pregnancy Childbirth
Thomsen M, Danielsen SE, Johannesen HL, Strøm M, Joensen MV, Veyhe AS.   +5 more
europepmc   +1 more source

Brain Health for Children

Brain Health, EarlyView.
ABSTRACT The World Health Organization (WHO) defines brain health as the maintenance of optimal brain integrity, good mental state, and cognitive function without significant neuropsychiatric disease. Early childhood is a critical period for brain development, which were influenced by early experiences, nutrition, and environmental factors. Disruptions
Yu Ma, Wenjuan Ma, Yue Jiang, Weiyi Chen, Yuanfeng Zhou, Yi Wang   +5 more
wiley   +1 more source

Relationship between prior pregnancy loss and subsequent adverse pregnancy outcomes in women. [PDF]

BMC Pregnancy Childbirth
Liu L, Zhang J, Wang R, Zhang W, Wang K, Wang F.   +5 more
europepmc   +1 more source

The Moderating Role of Strategic Investment in R&D and Advertising in Firms' ESG–Performance Relationship

Business Strategy and the Environment, EarlyView.
ABSTRACT This paper examines the association between environmental, social, and governance (ESG) ratings and firm performance, taking into account the role of firms' strategic investments in research and development (R&D) and advertising. Drawing on resource‐based view and signalling theory perspectives and employing the generalised method of moments ...
Syed Zulfiqar Ali Shah, Saeed Akbar, Sardar Ahmad   +2 more
wiley   +1 more source