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Adverse Reactions to Spironolactone
JAMA: The Journal of the American Medical Association, 1973To the Editor.— The recent report by Greenblatt and Koch-Weser (225:40, 1973) provides an important example of the difficulty of attempting to evaluate retrospectively the incidence and nature of adverse reactions to a specific drug. Such programs as the Boston Collaborative Drug Surveillance Program are certainly commendable in their intent, but the ...
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British Medical Bulletin, 1990
The elderly have benefitted considerably from the vast increase in the range of drugs available for prescription. However it is now well recognized that the incidence in adverse drug reactions increases with age. This is mainly due to altered pharmacodynamics and pharmacokinetics as well as multiple prescribing and the effect of illness rather than the
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The elderly have benefitted considerably from the vast increase in the range of drugs available for prescription. However it is now well recognized that the incidence in adverse drug reactions increases with age. This is mainly due to altered pharmacodynamics and pharmacokinetics as well as multiple prescribing and the effect of illness rather than the
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Postgraduate Medicine, 1965
The present trend toward polypharmacy increases the likelihood of adverse drug reactions and obscures the relationship of drugs to complications. Both host factors and drug factors predispose to the development of an adverse reaction. Reactions may be related to therapeutic or nontherapeutic effects of drugs. Other categories include allergic reactions
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The present trend toward polypharmacy increases the likelihood of adverse drug reactions and obscures the relationship of drugs to complications. Both host factors and drug factors predispose to the development of an adverse reaction. Reactions may be related to therapeutic or nontherapeutic effects of drugs. Other categories include allergic reactions
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