Results 21 to 30 of about 2,510,388 (303)

A New Criterion for Fluoroquinolone-Associated Disability Diagnosis: Functional Gastrointestinal Disorders

Medicina, 2021
Background and Objectives: Fluoroquinolones (FQs) are a broad-spectrum class of antibiotics routinely prescribed for common bacterial infections despite recent recommendations to use them only for life-threatening cases.
Deanna N. Cannizzaro, Lydia F. Naughton, Maya Z. Freeman, Linda Martin, Charles L. Bennett, Cecilia Bove   +5 more
doaj   +1 more source

SARS-CoV-2 vaccine excipients polyethylene glycol and trometamol do not induce mast cell degranulation, in an in vitro model for non-IgE-mediated hypersensitivity

Frontiers in Allergy, 2022
The development of vaccines against SARS-CoV2 brought about several challenges, including the management of hypersensitivity reactions to these formulations.
Paola Leonor Quan, Laia Ollé, Laia Ollé, Marina Sabaté-Brescó, Marina Sabaté-Brescó, Marina Sabaté-Brescó, Yanru Guo, Yanru Guo, Rosa Muñoz-Cano, Rosa Muñoz-Cano, Rosa Muñoz-Cano, Annette Wagner, Gabriel Gastaminza, Gabriel Gastaminza, Gabriel Gastaminza, Margarita Martín, Margarita Martín, Margarita Martín   +17 more
doaj   +1 more source

Clinical practice guidelines for translating pharmacogenomic knowledge to bedside. Focus on anticancer drugs.

Frontiers in Pharmacology, 2014
The development of clinical practice recommendations or guidelines for the clinical use of pharmacogenomics data is an essential issue for improving drug therapy, particularly for drugs with high toxicity and/or narrow therapeutic index such as ...
José A G Agúndez, José A G Agúndez, Gara eEsguevillas, Gara eEsguevillas, Gemma eAmo, Gemma eAmo, Elena eGarcía-Martín, Elena eGarcía-Martín   +7 more
doaj   +1 more source

Improving reporting of adverse drug reactions: Systematic review. [PDF]

, 2009
BACKGROUND: Adverse drug reactions (ADRs) are a significant cause of morbidity and mortality, with many being identified post-marketing. Improvement in current ADR reporting, including utility of underused or innovative methods, is crucial to improve ...
Molokhia, Mariam, Mariam Molokhia, Tanna, S, Molokhia, M, Bell, D, Bell, Derek, Derek Bell, Tanna, Shivani, Shivani Tanna   +8 more
core   +1 more source

Adverse drug reactions [PDF]

Clinical Medicine, 2016
Adverse drug reactions (ADRs) remain a challenge in modern healthcare, particularly given the increasing complexity of therapeutics, an ageing population and rising multimorbidity. This article summarises some of the key facts about ADRs and explores aspects relating to their prevention, diagnosis, reporting and management in current clinical practice.
Jamie J, Coleman, Sarah K, Pontefract
openaire   +4 more sources

Differences in Linear Epitopes of Ara h 9 Recognition in Peanut Allergic and Tolerant, Peach Allergic Patients

Frontiers in Allergy, 2022
BackgroundPeanut-allergic patients from the Mediterranean region are predominantly sensitized to the lipid transfer protein (LTP) Ara h 9, and the peach LTP Pru p 3 seems to be the primary sensitizer. However, LTP sensitization in peanut allergy is not a
L. Sánchez-Ruano, C. Fernández-Lozano, M. Ferrer, M. Ferrer, F. Gómez, F. Gómez, B. de la Hoz, B. de la Hoz, J. Martínez-Botas, J. Martínez-Botas, M. J. Goikoetxea, M. J. Goikoetxea   +11 more
doaj   +1 more source

Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998-2005. [PDF]

, 2007
BACKGROUND: Adverse drug reactions (ADRs) are a frequent cause of mortality and morbidity to patients worldwide, with great associated costs to the healthcare providers including the NHS in England.
Majeed, Azeem, Patel, M, Car, J, Molokhia, Mariam, Mariam Molokhia, Janakan Srishanmuganathan, Patel, H, Bell, Derek, Car, Josip; id_orcid, Srishanmuganathan, Janakan, Car, Josip, Majeed, A, Mitesh Patel, Patel, Hitesh, Josip Car, Bell, D, Molokhia, M, Patel, Mitesh, Derek Bell, Srishanmuganathan, J, Hitesh Patel, Azeem Majeed   +21 more
core   +2 more sources

Drug and xenobiotic biotransformation in the blood-brain barrier: A neglected issue.

Frontiers in Cellular Neuroscience, 2014
Drug biotransformation is a crucial mechanism for facilitating the elimination of chemicals from the organism and for decreasing their pharmacological activity.
José A.G. Agúndez, José A.G. Agúndez, Félix Javier eJiménez-Jiménez, Hortensia eAlonso-Navarro, Elena eGarcía-Martín, Elena eGarcía-Martín   +5 more
doaj   +1 more source

Appropriateness of red blood cell use in China in the last thirteen years: A systematic review

Heliyon, 2019
Objective: To determine both the rates of appropriate red blood cells (RBCs) use in China and where inappropriate use is particularly prevalent. Background: In China, obtaining the comprehensive picture in unnecessary RBCs transfusion is helpful for ...
Yujie Kong, Xiangming Wang, Yonghua Yin, Xue Tian, Ling Li, Jue Wang, Li Tian, Ning Song, Zhong Liu   +8 more
doaj   +1 more source

Anti-SARS-CoV-2 neutralizing monoclonal antibodies: clinical pipeline

mAbs, 2020
Monoclonal antibody (mAb) therapy has been previously exploited for viral infections, such as respiratory syncytial virus pneumonia and Ebolavirus disease.
Marco Tuccori, Sara Ferraro, Irma Convertino, Emiliano Cappello, Giulia Valdiserra, Corrado Blandizzi, Fabrizio Maggi, Daniele Focosi   +7 more
doaj   +1 more source