Results 121 to 130 of about 2,243,245 (285)

Thrombotic Microangiopathy‐Like Phenotype in Patients With Infection‐Associated Disseminated Intravascular Coagulation Treated With Thrombomodulin Alfa

European Journal of Haematology, EarlyView.
ABSTRACT Despite disseminated intravascular coagulation (DIC) and thrombotic microangiopathy (TMA) sharing features of thrombocytopenia, organ dysfunction, and bleeding, the relationship between these two conditions remains unclear. We therefore conducted a post hoc analysis of post‐marketing surveillance data from Japan to evaluate the clinical ...
Naoki Takezako, Fumiyo Komatsu, Goichi Honda, Noriaki Kawano, Toshimasa Uchiyama, Kazuo Kawasugi, Seiji Madoiwa, Kei Suzuki, Yoshinobu Seki, Takayuki Ikezoe, Kohji Okamoto, Hideo Wada   +11 more
wiley   +1 more source

Pattern and Prevalence of Acute and Delayed Transfusion Reactions Following Blood Component Therapy

Current Clinical and Medical Education
Introduction: The blood transfusion procedure is crucial from a therapeutic standpoint but may cause adverse effects to the patients through acute and delayed adverse transfusion reactions (ATRs).
Abhijeet Ramesh Dhawale, Prithviraj D Jaybhaye   +1 more
doaj  

FVIIIa Mimetics: New Approaches and Next‐Generation Initiatives

Haemophilia, EarlyView.
ABSTRACT Emicizumab has revolutionized hemophilia A care, yet limitations regarding the “ceiling” of hemostatic efficacy (equivalent to mild hemophilia) and global access persist. This review critically examines two distinct paradigms shaping the future of care: Innovation and Access. Regarding innovation, we synthesize the latest clinical data on next‐
Tadashi Matsushita, Keiji Nogami, Chandrakala Shanmukhaiah   +2 more
wiley   +1 more source

Clinical aspects of blood transfusion in cats [PDF]

, 2009
The safe use of transfusion therapy requires proper knowledge on blood groups, blood typing, donor selection, blood collection, transfusion protocols and adverse transfusion reactions.
Arıkan, Şevket, Arikan, Sevket, Gurkan, Mehmet   +2 more
core  

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Effects of Adipose Plasma Transfusion Compared with Normal Plasma Transfusion on Adverse Transfusion Reactions, Important Functional Indicators, and Clinical Safety in Patients with Parenteral Nutrition: Based on a Retrospective Cohort Study.

Evid Based Complement Alternat Med, 2022
Gong C, Qin X, Chen H, Wu X, Wu J, Li H, Wang W.   +6 more
europepmc   +1 more source

Real‐World Outcomes of Prophylaxis With rIX‐FP in Germany: A Prospective, Non‐Interventional Study in Haemophilia B

Haemophilia, EarlyView.
ABSTRACT Introduction Efficacy and safety of albutrepenonacog alfa (rIX‐FP) in people with haemophilia B (PwHB) has been previously demonstrated in clinical trials. However, real‐world data insights are required. Aim To describe real‐world effectiveness and tolerability of rIX‐FP in PwHB in Germany.
Johannes Oldenburg, Swee Wenning, Susanne Holzhauer, Wolfgang Miesbach, Robert Klamroth, Thomas Linhoff, Patrick Sommerer, Christian Pfrepper, Martin Olivieri, all study investigators   +9 more
wiley   +1 more source

A Study of Transfusion Related Adverse Events at a Tertiary Care Center in Central India: A Retrospective Evaluation

Journal of Medical Sciences and Health, 2016
Background: The goal of hemovigilance is to improve the safety and quality of blood transfusion services. An identification of adverse transfusion reactions (ATRs) will help to take appropriate steps to reduce their incidence and make blood transfusion ...
Riti Tushar Kanti Sinha1, Preeti Rai, Aniruna Dey   +2 more
doaj  

Pilot study to understand and compare challenges being faced in reporting of transfusion reactions in various types of blood banks enrolled under Haemovigilance Programme of India

Asian Journal of Transfusion Science
BACKGROUND: Hemovigilance has become one of the important quality check systems of blood transfusion process, but under/non-reporting of transfusion-associated adverse reactions despite the presence of reporting systems emphasize the need to understand ...
Rayaz Ahmad Bhat, Vishal Tiwari, Satyajeet Singh, Ruchi Rao, Akash Chaudhary, Akanksha Bisht   +5 more
doaj   +1 more source

Dilution‐Endpoint Comparison of a Flow Cytometric Platelet Activation Assay With PF4/Heparin ELISA and a Lateral Flow Immunoassay in Suspected HIT

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Heparin‐induced thrombocytopenia (HIT) is a rare but potentially life‐threatening, immune‐mediated adverse reaction to heparin. PF4‐dependent immunoassays are sensitive screening tests, but they detect both platelet‐activating and nonactivating antibodies; therefore, positive results require interpretation in clinical context and,
Elvira Maličev, Matjaž Urbajs, Katerina Jazbec Gradišar, Ana Kolenc, Primož Rožman   +4 more
wiley   +1 more source