Results 101 to 110 of about 29,889 (292)

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Incidence of Adverse Transfusion Reaction and Practices for its Prevention

Haematology International Journal, 2021
Transfusion reactions are the untoward event towards blood products. Although majority of transfusion reactions are uneventful sometimes it may have life threatening events. This study was conducted to estimate the incidence and determine the nature of blood transfusion reactions in our hospital.
openaire   +1 more source

A1vB Genotype With Weak A Antigen Expression: Resolution of an ABO Discrepancy Using Serological and Molecular Approaches

The Kaohsiung Journal of Medical Sciences, EarlyView.
Wan‐Hua Yang, Fen‐Cing Liou
wiley   +1 more source

Platelet function in patients undergoing major non‐cardiac vascular surgery (PLUGS): a prospective cohort study*

Anaesthesia, EarlyView.
Summary Introduction Patients who require major vascular surgery often receive antiplatelet therapy for primary or secondary prevention of cardiovascular disease. Clopidogrel resistance and variability in platelet recovery after drug discontinuation pose clinical challenges, particularly for regional anaesthesia and blood management.
Akshay Shah, Grace Polley, Kasia Bera, Keith Maher, Stephen Von‐Kier, Antonio Barbosa, Louis Corrigan, Sabeena Sharma, Peter Baker, Stuart R. McKechnie, Michael J. Desborough, on behalf of the PLUGS Investigators   +11 more
wiley   +1 more source

Sociodemographic Factors Related to Adverse Donor Reactions in Shenzhen

, 2023
Li-Yan Sun,1 Qiong Yu,2 Cai-Ming He,2 Song-Xing Wang3 1Institution of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, People’s Republic of China; 2Quality Control Department, Shenzhen Blood Center, Shenzhen, People’s Republic of China; 3Business ...
Wang SX, Sun LY, Yu Q, He CM
core  

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Blood Transfusion Reactions in Elderly Patients Hospitalized in a Multilevel Geriatric Hospital

Journal of Aging Research, 2014
Background/Objectives. Blood transfusion is a critical issue for patients with chronic diseases such as heart failure, chronic kidney disease, and malignancy. However, side effects are not rare.
E. Lubart, R. Segal, N. Tryhub, E. Sigler, A. Leibovitz   +4 more
doaj   +1 more source

Traceability of Blood Transfusions and Reporting of Adverse Reactions in Developing Countries: A Six-Year Postpilot Phase Experience in Burkina Faso.

, 2018
Traceability is an essential tool for haemovigilance and transfusion safety. In Burkina Faso, the implementation of haemovigilance has been achieved as part of a pilot project from 2005 to 2009.
Nana, Ashmed, Honorine Dahourou, Sawadogo, Salam, Nebie, Koumpingnin, Millogo, Tieba, Eléonore Kafando, Faber, Jean-Claude, Koumpingnin Nebie, Salam Sawadogo, Ashmed Nana, Dahourou, Honorine, Jean-Baptiste Tapko, Sontie, Sonia, Tapko, Jean-Baptiste, Jean-Claude Faber, Yonli, Dieudonné Yentema, Sonia Sontie, Deneys, Véronique, Véronique Deneys, Dieudonné Yentema Yonli, Tieba Millogo, Kafando, Eléonore   +21 more
core   +1 more source

The Panorama of Cerebral Palsy in Sweden Part XIV Shows Further Decrease in Prevalence and Severity in the Birth‐Years 2015–2018

Acta Paediatrica, EarlyView.
ABSTRACT Aim To describe prevalence, background and gross motor function of cerebral palsy (CP) in western Sweden 2015–2018 and compare to birth‐years 1999–2014. Methods Population‐based study covering 108 963 live births in 2015–2018. Birth characteristics, neuroimaging findings and motor outcome were analysed and prevalence calculated and compared to
Kate Himmelmann, Magnus Påhlman
wiley   +1 more source

Incidence and pattern of 12 years of reported transfusion adverse events in Zimbabwe: A retrospective analysis

, 2014
Background. Haemovigilance hinges on a systematically structured reporting system, which unfortunately does not always exist in resource-limited settings.
Mvere, David A., Postma, Maarten J., Khoza, Star, Chitiyo, McLeod E., Van Hulst, Marinus, Postma, Maarten J, Mvere, David A, Mafirakureva, Nyashadzaishe, Chitiyo, McLeod E, Van Hulst, Marinus; id_orcid, Postma, Maarten J.; id_orcid   +10 more
core   +1 more source