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Leukoreduction for the prevention of adverse reactions from allogeneic blood transfusion
A blood transfusion is an acute intervention, implemented to solve life and health-threatening conditions on a short-term basis. However, blood transfusions have adverse events, some of them potentially related to immune modulation or to a direct transmission of infectious agents (e.g. cytomegalovirus).
Daniel, Simancas-Racines +3 more
openaire +3 more sources
Suspected fibrosing cholestatic hepatitis in an immunocompetent child with hepatitis C: Case report
Abstract A 12‐year‐old boy presented to our center with elevated aminotransferases, jaundice, right upper quadrant tenderness, and hepatomegaly. Evaluation revealed a highly elevated blood hepatitis C virus (HCV) ribonucleic acid (RNA) level, and liver biopsy showed canalicular and intrahepatic cholestasis, feathery degeneration of hepatocytes, and ...
Sara Bohon +5 more
wiley +1 more source
Staff Responsibilities Flowchart for reporting a Transfusion Reaction
Each blood product transfused carries a small risk of an acute or late adverse event. The most common immediate adverse reactions are fever, chills and urticaria. The most potentially significant reactions include acute and delayed haemolytic transfusion
Blood Transfusion
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Blood Product Transfusion in Adults: Indications, Adverse Reactions, and Modifications
Millions of units of blood products are transfused annually to patients in the United States. Red blood cells are transfused to improve oxygen-carrying capacity in patients with or at high risk of developing symptomatic anemia.
Griggs, Joseph R +2 more
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Detection of Adverse Events of Transfusion in a Teaching Hospital in Ghana
Background and objectivesMonitoring the whole chain of events from the blood donors to recipients, documenting any undesirable or untoward effects and introducing measures to prevent their recurrence if possible, are components of haemovigilance systems.
Owusu-Ofori, A. K. +2 more
core +1 more source
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis despite surgical resection, yet the prognostic literature remains fragmented across hundreds of single‐institution studies that vary in design, covariates, and analytical approaches.
Muhammad Maisam Ali +8 more
wiley +1 more source
ASSESSMENT OF QUALITY OF LIFE, COMPLICATIONS AND POST-TRANSFUSION ADVERSE REACTIONS IN THALASSEMIA PEDIATRIC IN TERTIARY CARE HOSPITAL [PDF]
Objective: To assess the quality of life, investigate complications and adverse transfusion reactions post blood transfusion in thalassemia pediatric.Methods: A prospective, observational study was conducted over a period of six months in the pediatric ...
Najafzadeh, Ehsan +5 more
core +1 more source
ABSTRACT Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a major complication in women with epithelial ovarian cancer (EOC). We aimed to develop and externally validate an early postoperative risk score to identify EOC patients at increased risk of VTE after debulking surgery.
Qiu‐Lin Cui +6 more
wiley +1 more source
Modeling transfusion reactions and predicting in vivo cell survival with kodecytes.
The availability of suitable animal models is a limitation in research on transfusion reactions. KODE technology allows for the artificial attachment of incompatible blood group antigens, plus visualization and recovery constructs onto red blood cells ...
Caroline Oliver +5 more
core +1 more source
Hemophilia A: An Ideal Disease for Prenatal Therapy
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada +2 more
wiley +1 more source

