Results 61 to 70 of about 2,243,245 (285)

Knowledge, attitude, and practice of reporting transfusion reactions in hemovigilance among health-care professionals in a tertiary care teaching hospital of northern India

National Journal of Physiology, Pharmacy and Pharmacology, 2020
Background: Blood transfusion is a lifesaving procedure but has potential to cause adverse events. Hemovigilance is a program that ensures safety of transfusion reactions by monitoring every step of transfusion process from donor to recipient.
Rukhsana Chowdhary, Vijay Khajuria, Vineeta Sawhney   +2 more
doaj   +1 more source

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

American Journal of Hematology, EarlyView.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho, Hasrini Rini, Noy N. Kambuaya, Syawal Satria, Freis Candrawati, Putu A. I. Shanti, King Alexander, Benediktus Andries, Aisah R. Amelia, Anjana Rai, Kim A. Piera, Agatha M. Puspitasari, Ristya Amalia, Pak Prayoga, Leo Leonardo, Maulina Hafidzah, Theo Situmorang, Dewi S. Margayani, Desandra A. Rahmayenti, Pengxing Cao, Enny Kenangalem, Leily Trianty, Damian Oyong, Julie A. Simpson, Rintis Noviyanti, Pierre A. Buffet, Jeanne R. Poespoprodjo, Nicholas M. Anstey   +27 more
wiley   +1 more source

Red cell transfusion and alloimmunization in sickle cell disease

Haematologica, 2021
Red cell transfusion remains a critical component of care for acute and chronic complications of sickle cell disease. Randomized clinical trials demonstrated the benefits of transfusion therapy for prevention of primary and secondary strokes and ...
Grace E. Linder, Stella T. Chou
doaj   +1 more source

Ceftriaxone‐associated immune haemolytic anaemia: A patient‐level systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Ceftriaxone can cause acute haemolysis. Its clinical presentation, risk factors, and outcomes remain incompletely characterized. We conducted a systematic review of published cases with patient‐level data, following international guidelines and with registration in PROSPERO (CRD420261338709). Reports were identified through three bibliographic
Sonja Miotti, Giada Wyttenbach, Mario G. Bianchetti, Camilla Lavagno, Pietro Camozzi, Gregorio P. Milani, Renato Gualtieri, Sebastiano A. G. Lava, Pietro B. Faré, Simone Janett   +9 more
wiley   +1 more source

Acute Profound Hypotension Following Intraoperative Plasma Transfusion-A Case Series. [PDF]

Acta Anaesthesiol Scand
ABSTRACT Background Blood transfusions can be lifesaving but carry risks of serious adverse reactions, including the less recognized hypotensive transfusion reaction, characterized by hypotension that may be difficult to distinguish from other transfusion reactions or haemorrhage‐related shock.
Batz T, Nordström J, Hertzberg D, Brismar V, Kåhlin J, Hedberg M, Von Oelreich E, Jonsson Fagerlund M.   +7 more
europepmc   +2 more sources

Adverse Transfusion Reaction in Hospital Shah Alam

, 2020
Introduction Blood transfusion is a safe and effective way for replacing blood loss especially during surgery, trauma or bleeding disorder. However adverse transfusion reactions (TRs) do occur during or post transfusion, from mild to rarely severe form of reaction.
Intan Farhana Zainudin, Shuhada Abdul Halim, Suziana Mohamad Nasir, Hanan Mahmood   +3 more
openaire   +2 more sources

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

Biotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga, Udisha Singh, Sachin Dattram Pawar   +2 more
wiley   +1 more source

A telomere-related gene risk model for predicting prognosis and treatment response in acute myeloid leukemia

Heliyon
Acute myeloid leukemia (AML) is a prevalent hematological malignancy among adults. Recent studies suggest that the length of telomeres could significantly affect both the risk of developing AML and the overall survival (OS).
Hui-Zhong Shi, Ming-Wei Wang, Yu-Song Huang, Zhong Liu, Ling Li, Li-Ping Wan   +5 more
doaj   +1 more source

Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998-2005. [PDF]

, 2007
BACKGROUND: Adverse drug reactions (ADRs) are a frequent cause of mortality and morbidity to patients worldwide, with great associated costs to the healthcare providers including the NHS in England.
Majeed, Azeem, Patel, M, Car, J, Molokhia, Mariam, Mariam Molokhia, Janakan Srishanmuganathan, Patel, H, Bell, Derek, Car, Josip; id_orcid, Srishanmuganathan, Janakan, Car, Josip, Majeed, A, Mitesh Patel, Patel, Hitesh, Josip Car, Bell, D, Molokhia, M, Patel, Mitesh, Derek Bell, Srishanmuganathan, J, Hitesh Patel, Azeem Majeed   +21 more
core   +2 more sources

Antibody kinetics against tetanus toxoid before and after primary vaccination of foals

Equine Veterinary Journal, EarlyView.
Abstract Background Vaccination recommendations for foals against Clostridium tetani vary. Available studies assessing foal immune responses, maternal antibody interference, or individual variation often used small foal numbers. Objectives To quantify antibody responses after tetanus vaccination in foals and explore associations with passively ...
Katharina Olbrich, Monica Venner, Bettina Wagner   +2 more
wiley   +1 more source