Results 51 to 60 of about 2,243,245 (285)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Platelets in infection: intrinsic roles and functional outcomes
Frontiers in ImmunologyPlatelets have long been acknowledged for their essential roles in hemostasis and thrombosis; however, recent insights highlight their broader involvement as key participants in host responses during infection. Beyond their classical functions, platelets
Yuwei Hu +14 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
Zhongguo shuxue zazhi[Objective] To identify small molecule peptides specifically binding to RhE antigen via phage display technology, providing a theoretical basis to prevent RhE alloimmunization. [Methods] A peptide (FLWMFWPSVNSPLLRSPIQRKNA) with RhE antigen-specific amino
QIN Wei, LI Tong, TIAN Li
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Frontiers in ImmunologyBackgroundAcute myeloid leukemia (AML) is a hematopoietic malignancy with poor outcomes and high recurrence. Disulfidptosis, a novel form of programmed cell death driven by aberrant disulfide bonds and F-actin collapse, provides insights into cancer ...
Han Gong +12 more
doaj +1 more source
Advanced Science, EarlyView.Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang +4 more
wiley +1 more source
Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium
Advanced Science, EarlyView.Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed +12 more
wiley +1 more source
Transfusion reactions in neonates and pediatrics: How and why are they different?
Asian Journal of Transfusion Science, 2023 Neonates and children are physically as well as physiologically different from adults. They are immunologically vulnerable, and the effects of transfusion can be longstanding, including with respect to their development.
Abhishekh Basavarajegowda +1 more
doaj +1 more source
Macrophage GLUD1 is Essential for Redox Balance and Immune Homeostasis in Cardiac Injury
Advanced Science, EarlyView.Excessive free radical production and dysregulated immune responses are key contributors to myocardial ischemia‐reperfusion (IR) injury. Macrophage GLUD1 activity safeguards against HIF‐1α accumulation and maladaptive responses to IR‐induced ROS production.
Tingting Jin +16 more
wiley +1 more source