Results 151 to 160 of about 2,243,245 (285)

Breakthrough Hemolysis in Paroxysmal Nocturnal Hemoglobinuria: Mechanistic Insights and Management Strategies

open access: yesTransfusion, EarlyView.
Abstract Background Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell disorder caused by somatic mutations in the PIGA gene, resulting in loss of glycosylphosphatidylinositol (GPI)‐anchored proteins, including the complement regulatory proteins, CD55 and CD59.
Ganesh Raman   +4 more
wiley   +1 more source

Evaluation of an ABO antibody immunoadsorption column for reduction of anti‐A and anti‐B isoagglutinin titers in group O platelet units

open access: yesTransfusion, EarlyView.
Abstract Background Clinical guidelines recommend transfusing ABO‐identical platelets where possible. However, the short shelf life of platelets (5–7 days) and stock availability mean ABO‐nonidentical platelet transfusions are sometimes unavoidable. Minor ABO‐incompatible platelet transfusions carry a risk of hemolysis due to donor anti‐A/B antibodies,
Melanie J. Robbins   +5 more
wiley   +1 more source

Prehospital whole blood transfusion versus component therapy—A scoping review

open access: yesTransfusion, EarlyView.
Abstract Background Whole blood has gained a foothold over component therapy in civilian emergency care, especially in emergency departments. In a prehospital setting, whole blood might be the logistically easier alternative compared to component therapy. However, most previous studies have been conducted in the emergency room setting.
Laura Muurinen   +3 more
wiley   +1 more source

Prophylactic oral calcium–vitamin D3–magnesium supplementation reduced citrate‐related reactions during peripheral blood stem cell collection in healthy donors: A randomized controlled trial

open access: yesTransfusion, EarlyView.
Abstract Background Citrate‐related reactions remain the most common adverse events during peripheral blood stem cell (PBSC) collection despite routine prophylactic intravenous calcium administration. We evaluated whether prophylactic oral calcium–vitamin D3–magnesium supplementation reduces citrate‐related reactions in healthy PBSC donors.
Keiko Fujii   +8 more
wiley   +1 more source

UNDERREPORTING IN REPORTING SYSTEM FOR ADVERSE TRANSFUSION REACTIONS

open access: yesJapanese Journal of Transfusion and Cell Therapy, 2015
Noriaki Iwao   +19 more
openaire   +2 more sources

Development of a systematic drug screening method for cord blood donation for transfusion to extremely preterm neonates

open access: yesTransfusion, EarlyView.
Abstract Background Cord blood‐derived red blood cell transfusions (CB‐RBCs) are being developed for extremely preterm neonates to preserve physiological fetal hemoglobin levels. We assessed how standard blood donor medication screening could be adapted for this novel donor population.
Jip H. van Daelen   +12 more
wiley   +1 more source

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