Results 201 to 210 of about 2,243,245 (285)

Recombinant Human Thrombopoietin Reduces the Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia

American Journal of Hematology, Volume 101, Issue 10, Page 2571-2580, October 2026.
ABSTRACT Chronic liver disease (CLD)‐related thrombocytopenia can limit the feasibility of invasive procedures. Recombinant human thrombopoietin (rhTPO) has demonstrated a favorable safety profile without hepatotoxicity. We evaluated the efficacy and safety of rhTPO in patients with CLD‐related thrombocytopenia who were undergoing elective invasive ...
Yifan Han, Ning Lin, Jinghang Xu, Sikui Wang, Jinglan Jin, Jia Shang, Yongning Xin, Youwen Tan, Dazhi Zhang, Jinlin Hou, Ping An, Wen Xie, Yujuan Guan, Qingfang Xiong, Hong Wu, Huiguo Ding, Yu Chen, Rongkuan Li, Zhili Wen, Mingqin Lu, Jinhui Yang, Zhongyin Zhou, Yongjian Zhou, Zujiang Yu, Kecan Lin, Wei Wang, Yan Huang, Yuemin Nan, Xinhua Luo, Rongshu Shi, Yi Kang, Tao Han, Shiyan Chen, Kai Wang, Yunfeng Shan, Jiaping Li, Pingguo Liu, Zheng Lu, Jun Chen, Zhen Liu, Liaoyun Zhang, Li Yang, Jifang Sheng, Zhan Zeng, Yanyan Yu, Xiaoyuan Xu   +45 more
wiley   +1 more source

Intravenous vs Oral Iron for Treating Iron Deficiency Anemia in Pregnancy: A Systematic Review and Meta-Analysis.

JAMA Netw Open
Sales SK, Rajprohat S, Simon L, Hardi A, Stoll C, Benson AE, Shatzel JJ, Lo JO, Tuuli MG, Lewkowitz AK.   +9 more
europepmc   +1 more source

Umbilical cord blood infusion enhances hematopoietic recovery and improves survival in elderly AML patients with chemotherapy-induced myelosuppression: a retrospective study. [PDF]

Front Oncol
Zhou Y, Ren Y, Zhang L, Hu W, Ma J, Wang X.   +5 more
europepmc   +1 more source

Biologic and Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Do Not Arrest Bone Loss in Patients With Rheumatoid Arthritis: A Long‐Term Multicenter Observational Study

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2036-2049, October 2026.
Objective Osteoporosis causes fractures that further increase the disease burden of rheumatoid arthritis (RA); however, osteoporosis treatment rates remain low. Although several studies have reported that biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) can prevent or improve osteoporosis in RA, our large‐scale, real ...
Takafumi Aritomi, Koshiro Sonomoto, Shingo Nakayamada, Hiroaki Tanaka, Atsushi Nagayasu, Satoshi Kubo, Ippei Miyagawa, Ayako Yamaguchi, Naoaki Ohkubo, Yasuyuki Todoroki, Yurie Satoh‐Kanda, Masanobu Ueno, Ryuichiro Kanda, Yuya Fujita, Masashi Funada, Hidenori Sakai, Satsuki Matsunaga, Hiroaki Tanaka, Masayuki Shinojima, Hiroki Kawamura, Kazuki Takahashi, Miyabi Ando, Kazuki Haru, Yusuke Miyazaki, Kentaro Hanami, Masao Nawata, Shunsuke Fukuyo, Keisuke Nakatsuka, Mikiko Tokunaga, Kazuyoshi Saito, Yoshiya Tanaka   +30 more
wiley   +1 more source

Knowledge, Attitude, and Practices Related to Hemovigilance Among Healthcare Professionals: A Cross-Sectional Study. [PDF]

Cureus
Sharma R, Raina R, Rani S, Malhotra P.
europepmc   +1 more source

Evaluating effectiveness of risk minimization through healthcare professional surveys: A review of post‐authorization studies, 2022–2024

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3495-3502, October 2026.
Abstract Aims Risk minimization measures (RMMs) are key regulatory tools to ensure safe medicinal product use. Regulatory guidelines recommend pre‐specifying the targets, or ‘thresholds’, for assessing RMM effectiveness. We aimed to review recent industry‐sponsored post‐authorization safety studies (PASS) that evaluated the effectiveness of RMMs ...
Kexin Zhu, William A. Blumentals, Froilan G. Celzo, G. Caleb Alexander, Lingyun Zhou, Juhaeri Juhaeri, Corinne Jouquelet‐Royer, Jian‐Yu E   +7 more
wiley   +1 more source

Incidence, Clinical Characteristics, Management, and Outcomes of Hematologic Immune‐Related Adverse Events Associated With Immune Checkpoint Inhibitors: A Single‐Center Japanese Retrospective Cohort Study

Cancer Medicine, Volume 15, Issue 10, October 2026.
This single‐center retrospective study evaluated hematologic immune‐related adverse events (irAEs) among 3371 patients treated with immune checkpoint inhibitors. Forty patients developed hematologic irAEs (1.2%); 85.0% of events were Grade 3 or higher, and the median time to onset was 12 weeks.
Ryo Yoshimaru, Hirotaka Nakamura, Yong‐Mei Guo, Kensuke Matsuda, Tetsuya Sakai, Yoshitaka Zenke, Kiyotaka Yoh, Kohei Shitara, Nobuaki Matsubara, Kenichi Harano, Hiromichi Nakajima, Nobuyuki Takahashi, Masafumi Ikeda, Takao Fujisawa, Saki Nakamura, Kenta Akie, Masayuki Ito, Masashi Wakabayashi, Junichiro Yuda   +18 more
wiley   +1 more source

Development and Validation of a Checklist for Safe Blood Transfusion in Anesthesia: A Methodological Study. [PDF]

Health Sci Rep
Mahdizadeh S, Moradimajd P, Taghizadeh S, Abolghasemi J, Sedigh Maroufi S.   +4 more
europepmc   +1 more source

Low‐Dose Cytarabine Plus G‐CSF Induction in Pediatric M2 Acute Myeloid Leukemia: A Multicenter Study

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT This retrospective secondary analysis of the multicenter randomized CALS III‐AML18 trial evaluated the efficacy and safety of low‐dose chemotherapy (LDC) compared with standard‐dose chemotherapy (SDC) in children with M2 acute myeloid leukemia (AML‐M2). A total of 221 children were included, with 109 in the LDC arm and 112 in the SDC arm.
Wenxin Ou, Xiaohua Zhu, Jun Lu, Hongsheng Wang, Ning Liao, Yufeng Liu, Hua Jiang, Qi An, Xiaojun Yuan, Hailong He, Ningling Wang, Jixia Luo, Xiuli Ju, Qian‐Fei Wang, Minghua Yang, Cheng Cheng, Peifang Xiao, Liangchun Yang, Li Gao, Raul C. Ribeiro, Shaoyan Hu, Xiaowen Zhai   +21 more
wiley   +1 more source

Long-term safety and effectiveness of romiplostim in patients with refractory aplastic anemia: a nationwide, all-case, post-marketing surveillance study in Japan. [PDF]

Ann Hematol
Itagaki M, Kuwazawa H, Sasaki S, Matsuura M, Tanaka Y, Obara N.   +5 more
europepmc   +1 more source