Short‐chain fatty acids modulate anti‐ROR1 chimeric antigen receptor (CAR) T‐cell function in an intestinal adenocarcinoma‐on‐chip model. Butyrate and propionate reduce cytotoxicity, cytokine release, and infiltration by inducing a regulatory T‐cell phenotype and T‐cell exhaustion via histone deacetylase inhibition.
Valentin D. Wegner+5 more
wiley +1 more source
Toluene Di-Isocyanate in Industry. Operating and Medical Codes of Practice. A Report of the Isocyanate Sub-Committee of the British Rubber Manufacturers' Association Ltd. Health Advisory Committee [PDF]
Kate Williamson
openalex +1 more source
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth+10 more
wiley +1 more source
Advisory Committee on Immunization Practices Recommended Immunization Schedule for Children and Adolescents Aged 18 Years or Younger - United States, 2025. [PDF]
Issa AN, Wodi AP, Moser CA, Cineas S.
europepmc +1 more source
Update From the September 2022 Meeting of the Advisory Committee on Immunization Practices. [PDF]
Gaviria-Agudelo C+3 more
europepmc +1 more source
Mastering Proton Activities in Aqueous Batteries
Advanced aqueous batteries are promising alternatives for grid energy storage. Understanding and mastering the proton activities in aqueous electrolytes will guide the design of sustainable and long‐lasting aqueous batteries. This Perspective comments on the current understanding of the thermodynamic and kinetic perspectives of proton activities and ...
Leiting Zhang, Chao Zhang, Erik J. Berg
wiley +1 more source
Summary of the National Advisory Committee on Immunization (NACI) Statement: Updated guidance on human papillomavirus (HPV) vaccines. [PDF]
Forbes N+3 more
europepmc +1 more source
Report of the Joint Meeting of the Papers and Publications Advisory Committee and the Board of Editors [PDF]
Thomas E. King
openalex +1 more source
Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin+17 more
wiley +1 more source