Results 121 to 130 of about 88,696 (242)

Dengue Virus Molecular Targets and Antiviral Drug Development: Advances, Challenges and Therapeutic Perspectives

ChemistrySelect, Volume 11, Issue 33, 1 September 2026.
This narrative review analyzes DENV molecular targets, including structural proteins (C, prM/M, E), non‐structural components (NS1NS5), and host factors, alongside small‐molecule candidates in preclinical and clinical phases. Owing to high structural conservation, the NS2B‐NS3 protease and NS5 (RdRp/MTase) remain primary drug discovery focuses, while ...
Aryane Lucia da Silva Aguiar De Oliveira, José Arion Da Silva Moura, Pedro César de Souza, Marcelo Arthur Dias da Costa Santana, Matheus Vinicius Guimarães de Melo, Douglas Carvalho Francisco Viana, Marina Galdino Da Rocha Pitta, Isabella Luiza Ralph de Oliveira, Maira Galdino Da Rocha Pitta   +8 more
wiley   +1 more source

UJI RESISTENSI LARVA NYAMUK Aedes aegypti TERHADAP INSEKTISIDA GOLONGAN KARBAMAT DI KECAMATAN MEDAN DENAI

, 2020
Aedes aegypti merupakan nyamuk vektor utama penyebab penyakit Demam Berdarah Dengue (DBD). Berbagai macam upaya telah dilakukan untuk pengendalian nyamuk Aedes aegypti salah satunya dengan cara penyemprotan (fogging) insektisida karbamat. Penggunaan dari

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Design and Synthesis of a Potent, Cell Active Purine‐Based Amidoxime Against the Dengue Virus

ChemistrySelect, Volume 11, Issue 36, 22 September 2026.
Scaffold hopping from our previous indolazepinone hit exemplifies purine SP‐835G with DENV2 EC50 0.1 µM, CC50>100 µM, clogP 3.61. Docking studies support its amidine metabolite operates as an allosteric inhibitor of DENV(pro). A flexible ether linker appears pivotal for enhancing binding and activity.
Dimitrios Kiousis, Despoina Giannioti, Georgia Kalyva, Vasiliki Zogali, Maharah Binte Abdul Mahid, Kitti Wing Ki Chan, Minos‐Timotheos Matsoukas, Subhash G. Vasudevan, Gerasimos Rassias   +8 more
wiley   +1 more source

Climate Informed Dengue Prediction and Future Risk Under a Changing Monsoon Climate in Kerala, India

GeoHealth, Volume 10, Issue 9, September 2026.
Abstract Dengue fever has emerged as a major public health threat in India, with its burden projected to rise under climate change. This study investigates the influence of climate variability on dengue incidence in Kerala, a dengue hotspot in southern India, using 14 years of climate and dengue data (2006–2019).
Yacob Sophia, Mathew Koll Roxy, Surendranath Bindu Vaisakh, Pallipurathu Raghunathan Nair Sreelakshmi, Thekkumkara Surendran Anish, Pillaveetil Sathyadas Indu   +5 more
wiley   +1 more source

Political Animals: To Live & Die in More‐Than‐Human Worlds

American Anthropologist, Volume 128, Issue 3, Page 660-667, September 2026.
ABSTRACT What does it mean to live—and therefore die—in a more‐than‐human world? This review essay explores that question through reflections on teaching Political Animals: Species, Class, Race, and Gender, an undergraduate course that introduces students to scholarship on human‐nonhuman relations.
Luísa Reis‐Castro
wiley   +1 more source

Analyzing Upper Extremity Disability From Health‐Related Quality of Life in Chronic Chikungunya: A Biopsychosocial Approach

Journal of Evaluation in Clinical Practice, Volume 32, Issue 6, September 2026.
ABSTRACT Relevance to the Journal Responding to the Journal of Evaluation in Clinical Practice's emphasis on person‐centered care, this study examines how pain, functional capacity and vitality influence lived disability and rehabilitation needs in individuals with chronic chikungunya.
Raildo Oliveira da Silva Filho, Marynara Fabíola Silva Araújo, Andreia Ravinia do Nascimento Oliveira, Maria Eduarda Medeiros da Costa Figueiredo, Dimitri Taurino Guedes, Renata Newman Leite dos Santos Lucena, Leonildo Santos do Nascimento Junior, Thais Marques Lima, Eleazar Marinho de Freitas Lucena   +8 more
wiley   +1 more source

Ingestion of attractive toxic sugar baits containing ivermectin before and after blood feeding affects the biology and reproduction of Aedes aegypti (Diptera: Culicidae)

Medical and Veterinary Entomology, Volume 40, Issue 3, Page 551-559, September 2026.
Attractive toxic sugar bait containing ivermectin (ATSB‐IVM) ingestion markedly reduced blood feeding, survival, oviposition, egg production and larval hatching, with the strongest effects when baits were ingested before blood feeding. Timing of ingestion (48–96 h before or after blood feeding) shaped sublethal impacts across the first and second ...
Thais Alves de Moura, Alyne Cunha Alves Dias, Alexandre de Almeida e Silva   +2 more
wiley   +1 more source

Spermatogenesis in Aedes aegypti.

, 1966
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +1 more source

Aedes aegypti Eradication Program manual of operations. Part I. For inspectors, foremen, and area supervisors [PDF]

Eradication of the yellow fever mosquito (Aedes aegypti) from the United States, Puerto Rico and the Virgin Islands will: 1. Eliminate the hazards of epidemics of yellow fever and dengue; 2. Increase the effectiveness of continuing foreign quarantine; 3.

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Effect of blood meals and mating on biodemographic characteristics of Aedes albopictus

Physiological Entomology, Volume 51, Issue 3, Page 446-459, September 2026.
Lifespan did not differ between virgin and mated males and females. The number of blood meals (one and two) significantly reduced adult lifespan compared with those with no blood meal. The effect of the second blood meal doubled females' egg production and their reproductive output.
Georgios D. Mastronikolos, Nikos T. Papadopoulos   +1 more
wiley   +1 more source