Results 41 to 50 of about 5,234,237 (301)
Agriculture, 2023 The problem of emitter clogging has become the main obstacle restricting the application and promotion of drip irrigation technology. Studying the process of emitter clogging helps improve irrigation efficiency and save water resources. A large number of
Rui Li +8 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Engineering Applications of Computational Fluid MechanicsThe flood discharge head is getting higher in high dam construction, threatening the safety of hydraulic engineering. Accurate prediction of the nappe trajectory is needed to help guarantee safety through downstream strategies.
Junling He +4 more
doaj +1 more source
Frontiers in Physiology, 2021 Rationale: Reducing the respiratory rate during extracorporeal membrane oxygenation (ECMO) decreases the mechanical power, but it might induce alveolar de-recruitment. Dissecting de-recruitment due to lung edema vs.
Elena Spinelli +17 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Process Optimization of Khoy Wastewater Treatment Plant Aerated Lagoons in Cold Climate Conditions [PDF]
آب و فاضلاب, 2006 The efficiency of Khoy WWTP located in the cold region in northwest of Iran has been studied from April 2002 to April 2004. The efficiency of WWTP in different seasons has been compared.
Yousof Rahimi +2 more
doaj
Remote Sensing of Aerated Flows at Large Dams: Proof of Concept
Remote Sensing, 2021 Dams are important for flood mitigation, water supply, and hydroelectricity. Every dam has a water conveyance structure, such as a spillway, to safely release extreme floods when needed. The flows down spillways are often self-aerated and spillway design
Matthias Kramer, Stefan Felder
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Re-Aeration on Stepped Spillways with Special Consideration of Entrained and Entrapped Air
Geosciences, 2018 As with most high-velocity free-surface flows, stepped spillway flows become self-aerated when the drop height exceeds a critical value. Due to the step-induced macro-roughness, the flow field becomes more turbulent than on a similar smooth-invert chute.
Daniel B. Bung, Daniel Valero
doaj +1 more source