Results 51 to 60 of about 18,374 (266)
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Flow and Aeration Characteristics of Micro Bubble Jet Flow
In this study, a new micro bubble generator, i.e. nozzle, with a very simple construction is proposed newly and the behavior, such as velocity distribution and spread, of micro bubble jet flow is made clear by PIV and LDA measurements of velocity distribution. The new nozzle uses a very high velocity water jet flow having a large velocity gradient near
SHAKOUCHI, Toshihiko +4 more
openaire +2 more sources
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Aerated steel slag filter system performance study for pollutants removal from domestic wastewater
Nitrogen removal from wastewater often requires a highly cost of chemical treatment to prevent over loading of nutrient in effluent discharge to the surface water body. However, to remove nitrogen it requires a complex process. Therefore, the aim of this
Hamdan R., Ibrahim Izzati Izwanni
doaj +1 more source
QUALITY OF SECONDARY WASTEWATER TREATMENT AT ZENIEN WASTE WATER TREATMENT PLANT [PDF]
Zenien waste water treatment plant (wwtp) consists of flow measurement device, screens, pre-aeration unit, primary sedimentation tanks, grit chamber, activated sludge tanks which were supported with diffused aeration system, final sedimentation tanks ...
R. M. Abdrabu +2 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Effect of Height and Geometry of Stepped Spillway on Inception Point Location
Air entrainment in a stepped spillway is very important to protect the spillway from cavitation damage. The inception point is the location where air starts entering the non-aerated flow zone. The inception point location depends on different parameters,
Wuyi Wan, Awais Raza, Xiaoyi Chen
doaj +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Nature-based Solutions (NbS) for municipal wastewater treatment have emerged as sustainable alternatives to increase global access to sanitation. This study has analyzed the global distribution and key design characteristics of NbS over the past 30 years,
Juliano Rezende Mudadu Silva +5 more
doaj +1 more source

