Results 61 to 70 of about 20,455 (258)

Comparison of aerial surveys and pellet‐based distance sampling methods for estimating deer density

open access: yesWildlife Society Bulletin, 2012
Wildlife biologists require density estimates for white‐tailed deer (Odocoileus virginianus) to facilitate management. Aerial surveys are often used to obtain density estimates, but are subject to problems necessitating the consideration of novel ...
Rachael E. Urbanek   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Moose survey app for population monitoring

open access: yesWildlife Society Bulletin, 2017
We developed a smart phone app for hunters to report the number of moose (Alces alces) observed while hunting in Alberta, Canada, during 2012–2014. Excessive costs of aerial surveys often result in infrequent estimates of moose abundance, whereas hunter ...
Mark S. Boyce, Rob Corrigan
doaj   +1 more source

Snow survey by aerial photographs

open access: yesGeoJournal, 1972
On the occasion of the heavy snow fall in January, 1963 in Hokuriku district the Geographical Survey Institute started its snow surveys by aerial photographs on a scale of 1 : 20, 000. Snow depth was measured at snow fissures on the slopes or exposed snow sections near the water on the photographs, using Stereotope, the third order instrument.
openaire   +2 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Recent experience of surveying the spawning grounds of pacific salmons in the water bodies of Chukotka

open access: yesИзвестия ТИНРО, 2020
Aerial survey of the pacific salmon spawning grounds was conducted in the water bodies of Chukotka belonged to the Bering Sea basin (the Anadyr, Velikaya, Tumanskaya Rivers and Meinypilgyno lake-river system) in 2019, for the first time since 1992. Total
E. A. Shevlyakov, S. V. Shubkin
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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