Results 101 to 110 of about 1,578,040 (262)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Index to aerial photographs of Alamosa County, Colorado, 1941: set CWQ DD

, 2022
Scale 1:20,000.Set complete.Index to aerial photographs of Alamosa County, Colorado, taken in 1963.

core  

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Photograph: Blue Ridge Aerial Surveys, "Aerial View of Dulles Toll Road and Dulles Airport," July, 1970

, 2006
Image: Photo, black and white original; 10" x 8" (25.3 cm x 20.3 cm)Aerial view of Dulles Toll Road and Dulles Airport taken by Blue Ridge Aerial Surveys on July 1970.
Blue Ridge Aerial Surveys
core   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Combining UAVs and multi-sensor dataloggers to estimate fine-scale sea turtle density at foraging areas: a case study in the central Mediterranean

Endangered Species Research
Knowledge of the distribution and density of marine species is key to understanding habitat use and interactions with human activities. Yet such information for sea turtles remains scarce, especially at foraging areas, where low turtle density represents
C Agabiti, L Tolve, G Baldi, M Zucchini, S Tuccio, F Restelli, D Freggi, P Luschi, P Casale   +8 more
doaj   +1 more source

Photograph: Blue Ridge Aerial Surveys, "Aerial View of Reston International Center Construction," November 24, 1971

, 2006
Image: Photo, black and white original; 10" x 8" (25.3 cm x 20.3 cm)Aerial view of the construction of Reston International Center taken by Blue Ridge Aerial Surveys on November 24, 1971. The Reston International Center can be seen near the center of the
Blue Ridge Aerial Surveys
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Aerial surveys of waterbirds in Australia. [PDF]

Sci Data, 2020
Kingsford RT, Porter JL, Brandis KJ, Ryall S.   +3 more
europepmc   +1 more source