Results 121 to 130 of about 311,057 (356)

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

open access: yesAdvanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong   +12 more
wiley   +1 more source

Carnosinase-1 overexpression, but not aerobic exercise training, affects the development of diabetic nephropathy in BTBR ob/ob mice [PDF]

open access: bronze, 2020
Inge Everaert   +15 more
openalex   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li   +8 more
wiley   +1 more source

Effect of Aerobic and Non-aerobic Exercises on Anxiety [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2006
troduction: Based on previous studies, exercise has an important role on the reduction of anxiety. Considering high rate of anxiety in youths and its negative effects on educational progress the present study was designed to investigate the effects of ...
M Pourranjbar, K Nematolah zadeh mahani
doaj  

The Effects Of Cognitively Engaging Physical Activity On The Executive Function Of Sixth Graders [PDF]

open access: yes, 2014
This purpose of this study was to examine the effects of cognitively engaging exercise, aerobic exercise, and resting conditions on the executive function of 6th graders.
Humphreys, Alyssa Michele
core   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

Effects of Combining Shockwaves or Radiofrequency with Aerobic Exercise on Subcutaneous Adipose Tissue and Lipid Mobilization: A Randomized Controlled Trial

open access: yesObesities
Reducing abdominal subcutaneous fat is a common concern among women, with evidence suggesting that combining aerobic exercise with external shock waves or radiofrequency may enhance fat reduction. This study aimed to assess the effects of six sessions of
Leila Marques   +7 more
doaj   +1 more source

Promoting Motor Cortical Plasticity with Acute Aerobic Exercise: A Role for Cerebellar Circuits

open access: yesNeural Plasticity, 2016
Acute aerobic exercise facilitated long-term potentiation-like plasticity in the human primary motor cortex (M1). Here, we investigated the effect of acute aerobic exercise on cerebellar circuits, and their potential contribution to altered M1 plasticity
Cameron S. Mang   +5 more
doaj   +1 more source

Deletion of growth hormone receptor in hypothalamic neurons affects the adaptation capacity to aerobic exercise

open access: green, 2020
João A.B. Pedroso   +7 more
openalex   +2 more sources

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