Results 101 to 110 of about 300,349 (305)

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

open access: yesAdvanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu   +16 more
wiley   +1 more source

PENGARUH OLAHRAGA AEROB RUTIN TERHADAP ATENSI MAHASISWA FK UNDIP YANG DIUKUR DENGAN ATTENTION NETWORK TEST [PDF]

open access: yes, 2015
Background: WHO stated that the lack of physical activity has been identified as a risk factor that causes the fourth 3.2 million deaths per year globally.
Indraswari, Darmawati Ayu   +2 more
core  

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

The comparison between effects of Berberis vulgaris Extract and aerobic exercise on none-alcoholic fatty liver in male rat [PDF]

open access: yes, 2016
The aim of this study was to evaluate the effects of Berberis vulgaris extract, aerobic exercise or their combination on the indicators of fatty liver, including serum C-reactive protein (CRP) and serum alanine aminotransferase (SGPT) in Wistar rats ...
Rafieian-Kopaei, Mahmoud.   +2 more
core  

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu   +8 more
wiley   +1 more source

Aerobic exercise repairs neurological function after cerebral ischaemia by regulating the nitric oxide

open access: yesAnais da Academia Brasileira de Ciências
: To investigate the mechanism of different exercise patterns on neurological function after focal cerebral ischaemia in rats. Rats with focal cerebral cerebral ischaemia were randomly divided into an aerobic exercise group, an exhaustive exercise group ...
LEI SUN, LV-PING ZHUANG, WEI-FENG WU
doaj   +1 more source

Does aerobic exercise improve or impair cardiorespiratory fitness and health among cleaners? A cluster randomized controlled trial

open access: yesScandinavian Journal of Work, Environment & Health, 2015
OBJECTIVE: It is unknown if aerobic exercise overloads or improves the cardiovascular system among workers with high occupational physical activity. This was investigated in a worksite randomized controlled trial (RCT) of aerobic exercise among cleaners.
Mette Korshøj   +6 more
doaj   +1 more source

Cancer‐Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT‐ANGPTL4 Axis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu   +20 more
wiley   +1 more source

Pengaruh Latihan Aerobic Dan Bicycle Crunch Terhadap Penurunan Lingkar Perut [PDF]

open access: yes, 2018
The habit of consuming fast food and exceeding the needs of his body impact on fat accumulation in the stomach. Excess abdominal fat is a risk factor for the development of heart disease and other obesity-related diseases.
, Isnaini Herawati S.Fis., M.Sc   +1 more
core   +2 more sources

A Survey of California Nurse Practitioners\u27 Health Practices and Counseling Habits [PDF]

open access: yes, 2005
Morbidity and mortality due to obesity continues to rise in the United States despite well known Healthy People 2010 and American College of Sports Medicine guidelines on physical activity. In the U.S.
Malone, Jessica
core   +1 more source

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