Results 61 to 70 of about 275,063 (307)

Comparison the effect of eight weeks aerobic training with moderate and high intensities on serum levels of Irisin and Uncoupling Protein 1 (UCP-1) in white adipose tissue in obese male rats

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2018
Background and Objective: The synthesis of uncoupling protein 1 (UCP1) in adipose tissue plays an important role in providing resistance and prevention of fat accumulation, weight gain and obesity.
Keyvan Hejazi   +4 more
doaj  

DAMPAK METODE LATIHAN PERMAINAN TERHADAP PENINGKATAN DAYA TAHAN AEROBIC: Studi Eksperimen Pada Atlet Sepakbola Usia Dini 12-15 Tahun Di Klub Arda Junior [PDF]

open access: yes, 2015
Skripsi ini dilatarbelakangi oleh pengamatan penulis terhadap beberapa metode latihan yang digunakan untuk meningkatkan daya tahan aerobic pada atlet sepak bola usia dini.
Muhanaf, Saeful
core  

The effect of exercise interventions on inflammatory biomarkers in healthy, physically inactive subjects: a systematic review [PDF]

open access: yes, 2017
Background: Increases in physical activity ameliorate low-grade systemic inflammation in disease populations such as type 2 diabetes mellitus and coronary artery disease.
Cronin, Owen   +3 more
core   +1 more source

Elevated TRIM25 Impairs Poly (ADP‐ribose) Metabolism via PARG Degradation and Mediates Compression‐Induced Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
TRIM25 acts as a multifunctional hub driving intervertebral disc degeneration under mechanical stress. Mechanical compression significantly upregulates TRIM25 expression, establishing it as a key E3 ubiquitin ligase platform. TRIM25 targets PARG and Ku80 via distinct molecular interfaces, triggering their ubiquitination and degradation.
Zhangrong Cheng   +9 more
wiley   +1 more source

The Role of Chemistry Across Disciplines From Humanities to Life Sciences in Understanding Complexity and Emergence

open access: yesAngewandte Chemie, EarlyView.
This study explores the origins of life by linking prebiotic chemistry, the emergence of information‐carrying molecules such as RNA and proteins, and philosophical questions about consciousness. The study emphasizes the role of molecular evolution in the Central Dogma and provides insights into the chemical origins of biology and the basis of life's ...
Harald Schwalbe   +5 more
wiley   +2 more sources

Effects of endurance versus strength training programs in the lipid profile of sedentary young adults [PDF]

open access: yes, 2017
Introduction Cardiovascular diseases are a major cause of mortality in the world, and abnormal blood lipids are an important risk factors for these disease (Stampfer et al., 2000).
Batalha, Nuno   +3 more
core   +2 more sources

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

open access: yesAdvanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao   +8 more
wiley   +1 more source

Near‐Infrared‐Light‐Driven Photochemistry and Photocatalysis: Mechanisms, Recent Applications, and Opportunities in Organic Synthesis and Biology

open access: yesAngewandte Chemie, EarlyView.
This minireview highlights recent advances in catalyst development and mechanistic strategies that enable photochemical and photocatalytic reactivity under 700–1000 nm NIR light, emphasizing how long‐wavelength excitation expands opportunities in both synthetic chemistry and biology.
Santosh K. Pagire   +3 more
wiley   +2 more sources

Aerobic training for improved memory in patients with stress-related exhaustion: a randomized controlled trial

open access: yesBMC Psychiatry, 2017
Background Patients with stress-related exhaustion suffer from cognitive impairments, which often remain after psychological treatment or work place interventions. It is important to find effective treatments that can address this problem. Therefore, the
Therese Eskilsson   +4 more
doaj   +1 more source

Exercise intolerance and fatigue in chronic heart failure: is there a role for group III/IV afferent feedback? [PDF]

open access: yes, 2020
Exercise intolerance and early fatiguability are hallmark symptoms of chronic heart failure. While the malfunction of the heart is certainly the leading cause of chronic heart failure, the patho-physiological mechanisms of exercise intolerance in these ...
Angius, Luca, Crisafulli, Antonio
core   +2 more sources

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