Results 51 to 60 of about 163,328 (242)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Aerodynamic design optimization using flow feature parameterization

open access: yes, 2007
Design optimization methods using high-fidelity computational fluid dynamics simulations are becoming increasingly popular in the area of aerodynamic design, sustaining the desire to make these methods more computationally efficient.
Barrett, Thomas Robin
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Aerodynamic noise from a train pantograph

open access: yes, 2014
Many studies have shown that when the speed of high speed trains exceeds around 300km/h, aerodynamic noise becomes the most significant noise source. The pantograph, or current collector, is mounted on the top of the train and is therefore not shielded ...
Liu, Xiaowan   +3 more
core   +1 more source

Numerical Study on Aerodynamic and Aeroacoustic Performances of Bioinspired Wings

open access: yesApplied Bionics and Biomechanics, 2023
Noise control has become one of the key issues to be considered in modern aeronautical machinery design. Many efforts have been devoted to noise reduction of airfoils and wings, including traditional flow control methods.
Dichen Li, Chuang Wei
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Three-dimensional large-scale aerodynamic shape optimization based on shape calculus [PDF]

open access: yes, 2013
Large-scale three-dimensional aerodynamic shape optimization based on the compressible Euler equations is considered. Shape calculus is used to derive an exact surface formulation of the gradients, enabling the computation of shape gradient information ...
Schmidt, Stephan   +4 more
core   +1 more source

Aeroelastic Effects on the Internal Flow Characteristics and Performance of the S-Shaped Inlet Duct

open access: yesApplied Sciences
The S-shaped inlet is increasingly used in modern aviation for its compact layout and stealth benefits, but its complex geometry induces strong pressure gradients and secondary flows that impact performance. Existing studies on S-shaped inlets are mostly
Daxin Liao   +6 more
doaj   +1 more source

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