Results 51 to 60 of about 1,291,837 (284)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Investigation of the Aerodynamic Characteristics of a Small Horizontal Wind Turbine Blade with Open-Source Software Using Advanced Turbulence Modelling

open access: yesChemical Engineering Transactions, 2021
Harvesting wind energy with wind turbine utilization is very important for the renewable sources industry. The maximization of a wind turbine efficiency is closely linked to the air flow characteristics around the wind turbine blades.
Thomas Nikou   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Experimental Study of Aerodynamic and Bird Exclusion Characteristics of a Branched Turboprop Inlet Under Ground Suction Conditions

open access: yesAerospace
A turboprop aircraft is exposed to the risk of bird strikes during flight, which may have a serious impact on flight safety once the bird is sucked into the engine. In this study, the aerodynamic and bird exclusion characteristics of a branched turboprop
Ge Zhou, Zhenlong Wu, Huijun Tan
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Numerical investigation for the influence of the car underbody on aerodynamic force and flow structure evolution in crosswind

open access: yesAdvances in Mechanical Engineering, 2018
To investigate the aerodynamic behavior of underbody structure in crosswind conditions, two numerical simulation models have been developed by using computational fluid dynamics method.
Zhiqun Yuan   +3 more
doaj   +1 more source

Combination resonance and primary resonance characteristics of a dual-rotor system under the condition of the synchronous impact of the inter-shaft bearing

open access: yesScientific Reports, 2023
The internal structure of many aero-engines is designed with a dual-rotor system. Up to now, there have been few studies on the influence of aerodynamic excitation on the dual-rotor system.
Guanshu Zuo   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy