Results 101 to 110 of about 38,138 (315)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
AerospaceThis work presents a method for simulating balanced gliding trajectories of high-hypersonic flight vehicles, circumventing the challenges associated with trajectory modeling for these advanced vehicles.
Guoxu Feng +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Aerodynamic circulation control for flapless flight control of an unmanned air vehicle [PDF]
, 2009 The supporting Flight Dynamics research contribution to the design of Demon, a flapless UAV demonstrator which is the subject of the national research programme FLAVIIR, is described in this thesis. In particular, an integrated flight control and fluidic
Buonanno, Annalisa
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Fuselage Aerodynamic Prediction Methods
, 2015 A CFD-based method to predict longitudinal and lateral-directional aerodynamic coefficients of an aircraft fuselage has been developed. A reliable aerodynamic characteristic estimation is crucial in order to carry out a well-designed aircraft.
Danilo Ciliberti +9 more
core +1 more source
CFD Investigation of the Effect of the Salient Flow Features in the Wake of a Generic Open-Wheel Race Car [PDF]
, 2015 It is well known that in motorsport the wake from an upstream vehicle can be detrimental to the handling characteristics of a following vehicle, in particular in formulae with high levels of downforce.
Newbon, Joshua +2 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
A numerical study on aerodynamic resonance in transonic separated flow
, 2009 An ongoing numerical investigation of unsteady shock/boundary layer interaction on a 2-d supercritical airfoil in transonic flow is presented. Initially, the finitevolume URANS solver DLR-TAU is used to simulate self-sustained periodic shock oscillations
Nitzsche, Jens
core