Results 111 to 120 of about 38,138 (315)

Wake dynamics and rotor-fuselage aerodynamic interactions

open access: yes, 2009
The unsteady loads experienced by a helicopter are known to be strongly influenced by aerodynamic interactions between the rotor and fuselage; these unsteady loads can lead to deficiencies in handling qualities and unacceptable vibratory characteristics ...
Brown, R.E., Kenyon, A.R.
core   +1 more source

Optimizing the Aerodynamic Performance of a Duct–Rotor System for Drones: A Comprehensive Study on the Coupled Parameters

open access: yesDrones
The integrated ducted structure significantly enhances the aerodynamic performance of the duct–rotor system, reducing noise and enhancing rotor safety. However, in the duct–rotor system, the coupled parameters of the rotor and the duct are crucial to its
Wei Wei   +8 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Optimal design of a flying-wing aircraft inner wing structure configuration [PDF]

open access: yes, 2012
Flying-wing aircraft are considered to have great advantages and potentials in aerodynamic performance and weight saving. However, they also have many challenges in design.
Huang, Haidong
core  

Aerodynamic characteristics and genesis of aggregates at Sakurajima Volcano, Japan. [PDF]

open access: yesSci Rep, 2022
Vecino MCD   +9 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

The feasibility of a road vehicle mounted aerodynamic testing apparatus

open access: yes, 2011
A ground vehicle mounted aerodynamic testing apparatus has been identified as a candidate concept for a low-cost alternative to traditional techniques.
Adams, Jordan
core  

The effect of rapid maxillary expansion on the upper airway's aerodynamic characteristics. [PDF]

open access: yesBMC Oral Health, 2021
Feng X   +4 more
europepmc   +1 more source

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