Results 51 to 60 of about 147,531 (294)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

THE AERODYNAMIC ANALYSIS OF THE PROFILES FOR FLYING WINGS [PDF]

open access: yesJournal of Defense Resources Management, 2013
The possibility of using an un-piloted aerial vector is determined by the aerodynamic characteristics and performances. The design for a tailless unmanned aerial vehicles starts from defining the aerial vector mission and implies o series of geometrical ...
Vasile PRISACARIU
doaj  

Aerodynamic Characteristics of Swept Propellers

open access: yesJournal of the Japan Society for Aeronautical and Space Sciences, 1984
The vortex lattice method is applied to calculations of the aerodynamic characteristics of propellers. A blade of the propeller is divided into many trapezoidal panels, and each panel is represented by a spiral horse shoe vortex in which a bound vortex is placed on the 1/4chord line of the panel, and a pair of wake vortices is emitted from the both ...
Makoto KOBAYAKAWA   +4 more
openaire   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Aerodynamic Characteristics of Airfoil Using Panel Method [PDF]

open access: yes, 2016
Potential flow over an airfoil plays an important historical role in the theory of flight. The governing equation for potential flow is Laplace\u27s equation, a widely studied linear partial differential equation. One of Green\u27s identities can be used
Junaidin, B. (Buyung)
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Analysis of aerodynamic characteristics of hypersonic folding-wing aircraft

open access: yesHangkong gongcheng jinzhan
Hypersonic aircraft encounter challenges in adapting to complex external environments during missions. Conventional fixed-wing aircraft have limited optimal aerodynamic performance under specific conditions.
WU Zaoping, QIN Jian, WU Jie
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The Aerodynamic Characteristics of Road Vehicles Overtaking on Bridge Deck under Crosswinds

open access: yesAdvances in Civil Engineering, 2020
The aerodynamic characteristics of road vehicles in windy environments are the prerequisites for the evaluation and prediction of the driving safety and stability.
Ning Chen   +3 more
doaj   +1 more source

Nonlinear Feedback Control of Axisymmetric Aerial Vehicles [PDF]

open access: yes, 2014
We investigate the use of simple aerodynamic models for the feedback control of aerial vehicles with large flight envelopes. Thrust-propelled vehicles with a body shape symmetric with respect to the thrust axis are considered.
Hamel, Tarek   +3 more
core   +3 more sources

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