Results 221 to 230 of about 4,272 (296)

Computation of aerodynamic damping for wind turbine applications [PDF]

open access: yes, 2002
Bertagnolio, F.; id_orcid 0000-0001-9271-709X   +4 more
openaire  

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan   +11 more
wiley   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

open access: yesAdvanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak   +6 more
wiley   +1 more source

Breaking the Trade‐Off of Mechanical Robustness and Energy Storage Capacity in Phase Change Materials Through a Molecular Design Strategy of Hard‐Segment‐Anchored/Side‐Chain‐Storage

open access: yesAdvanced Science, EarlyView.
To decouple mechanical robustness and energy storage capacity in phase change materials (PCMs), a series of polyurethane‐based PCMs bearing crystallizable alkyl side chains are synthesized via a hard‐segment‐anchored/side‐chain‐storage molecular design.
Huizhou Luo   +6 more
wiley   +1 more source

A Novel Proposal for a Bladeless Wind Turbine: Bio-Inspired Design of a Columnar-Cactus Type Mast. [PDF]

open access: yesBiomimetics (Basel)
Hernández-Arriaga I   +5 more
europepmc   +1 more source

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen   +22 more
wiley   +1 more source

Biomimetic Hydrogel System Targeting S100A8 Centered Neuroimmune Crosstalk and Hypoxia Induced Neuronal Injury

open access: yesAdvanced Science, EarlyView.
A biomimetic hydrogel (HPC@Gel) was developed for traumatic brain injury repair by combining oxygen‐carrying hemoglobin nanoparticles and anti‐inflammatory carbon quantum dots within a brain‐like matrix. The system alleviated hypoxia, reduced harmful neuroimmune signaling, protected neurons, supported neural regeneration, and improved neurological and ...
Peng Liu   +12 more
wiley   +1 more source

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