Results 51 to 60 of about 46,505 (316)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Rod–Airfoil Interaction Noise Reduction Using Gradient Distributed Porous Leading Edges

Applied Sciences, 2022
Rod–airfoil interaction noise is a major concern in several practical industrial and aeronautical applications. In this study, we constructed bio-inspired gradient distributed porous leading edges to reduce rod–airfoil interaction noise. Noise radiations
Yong Wang, Fan Tong, Zhengwu Chen, Chao Wang, Shujie Jiang   +4 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Study on Aerodynamic Shape Optimization for Wing of Business Jet

Hangkong gongcheng jinzhan, 2022
With the development of world economy and trade,the medium business jets are more favored by customers. In order to further improve the general aerodynamic performance of high-speed turbofan business jet,the optimization methods based on the full ...
MA Xiaoyong, WU Junqiang, XIAO Yunlei, ZHANG Yanjun, CHENG Zhihang, QIN Hejun, MIAO Shuai   +6 more
doaj   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Topology optimisation: increasing the speed and reliability of design [PDF]

, 2014
In this paper, topology optimisation is applied to the design of the rear fuselage of an unmanned aerial vehicle (UAV). A comparison is drawn between the performance of a design created through evolutionary structural optimisation (ESO) and a baseline ...
Andy Keane, Keane, Andy J., Sobester, Andras, Liam M. Kelly, Andras Sobester, Kelly, Liam, David Toal, Toal, David J.J.   +7 more
core   +1 more source

Effectiveness of a Novel Low‐Density Lipoprotein Apheresis Device Rheocarna in Patients Undergoing Hemodialysis With Chronic Limb‐Threatening Ischemia: A Single‐Center Retrospective Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic limb‐threatening ischemia (CLTI) is a severe form of lower‐extremity artery disease characterized by distal lesions and microcirculatory impairment, limiting revascularization efficacy. Rheocarna is a direct hemoperfusion low‐density lipoprotein (LDL) adsorption device with potential rheological and anti‐inflammatory ...
Kunihiro Ishioka, Takayasu Ohtake, Kei Ohmori, Chika Shibuya, Tomoki Tsukahara, Mizuki Yamano, Yasuhiro Mochida, Machiko Oka, Kyoko Maesato, Yusuke Tsukamoto, Hidekazu Moriya, Sumi Hidaka, Shuzo Kobayashi   +12 more
wiley   +1 more source

Three-dimensional large-scale aerodynamic shape optimization based on shape calculus

, 2013
Large-scale three-dimensional aerodynamic shape optimization based on the compressible Euler equations is considered. Shape calculus is used to derive an exact surface formulation of the gradients, enabling the computation of shape gradient information ...
Schmidt, Stephan, Ilic, Caslav, Gauger, Nicolas, Schulz, Volker, Gauger, Nicolas Ralph   +4 more
core   +1 more source

Investigation on the influence of aerodynamic characteristics of GAW-1 two-element airfoil with slot

Hangkong gongcheng jinzhan
As a passive flow control technology，airfoil slotting has the characteristics of simple structure and high efficiency in improving stall. CFD method is used to study the slotting of GAW-1 two-element airfoil to explore the influence of slot parameters on
ZHANG Zhihao, HAO Lishu, GAO Yongwei, LYU Wenhao   +3 more
doaj   +1 more source