Results 81 to 90 of about 9,345,647 (234)

Explicit modelling of lift characteristics for high-lift devices based on knowledge-guided symbolic regression using large language model

open access: yesEngineering Applications of Computational Fluid Mechanics
The High-Lift Device (HLD) plays a critical role in determining the low-speed aerodynamic performance of aircraft during takeoff and landing phases.
Yiheng Wang   +5 more
doaj   +1 more source

Experimental investigation on the optical emission spectroscopy of dielectric barrier discharge plasma actuators at different atmospheric pressures

open access: yesAIP Advances, 2018
The experiment of dielectric barrier discharge (DBD) plasma actuator using an asymmetrical electrodes configuration is conducted to investigate optical emission spectroscopy of the plasma discharge at pressures from 0.02 to 0.1 Mpa in air mixed with ...
S. Y. Xu, L. Kang, J. S. Cai, S. J. Tang
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Approximated models for aerodynamic coefficients estimation in a multidisciplinary design environment [PDF]

open access: yes, 2011
In this paper variable fidelity analyses are investigated. Moreover different kind of approximations to be used in a wide multidisciplinary design environment for aircraft design are built.
Tosetti, Marco   +2 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Three-dimensional large-scale aerodynamic shape optimization based on shape calculus [PDF]

open access: yes, 2013
Large-scale three-dimensional aerodynamic shape optimization based on the compressible Euler equations is considered. Shape calculus is used to derive an exact surface formulation of the gradients, enabling the computation of shape gradient information ...
Schmidt, Stephan   +4 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Research on wind tunnel test of low-speed characteristics optimization in Kink area of transport aircraft wings

open access: yesHangkong gongcheng jinzhan
For conventionally laid out civil transport aircraft in low-speed condition and high lift configurations, the advance of the stall angle of attack causes the aircraft's approach speed to be too high, it is necessary to optimize the low-speed ...
YAN Wei   +9 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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