Results 141 to 150 of about 90,246 (309)
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
A Review on Aerodynamics of Non-Flapping Bird Wings
Journal of Aerospace Technology and Management, 2016 Birds are known for their agility, manoeuvrability, and flexibility during flight. These features allow their ability to fly under a large range of flight conditions. Bio flyers and bio aerodynamic/fluid surfaces have inspired many to perform experiments
Mohammed Abdulmalek Aldheeb +3 more
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Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source
AERODYNAMIC INTERACTION OF TWO VEHICLES IN SELECTED DRIVE MODES
Perner’s Contacts, 2010 Numerical simulation of two vehicles aerodynamical interaction in selected drive modes in this paper will be described.
Lukáš Kutěj, Michal Richtář
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Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Aerodynamic interaction between vortical wakes and lifting two-dimensional bodies [PDF]
Unsteady rotor wake interactions with the empennage, tail boom, and other aerodynamic surfaces of a helicopter have a significant influence on its aerodynamic performance, the ride quality, and vibration.
Stremel, Paul M.
core +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
2-D CFD Computations of the Two-Bladed Darrieus-Type Wind Turbine
Journal of Applied Fluid Mechanics, 2018 In spite of the attractiveness of CFD methods and advanced measurement methods, there is still no full analysis of aerodynamic blade loads for vertical axis Darrieus-type wind turbines.
K. Rogowski, M. O. L. Hansen, P. Lichota
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