Results 151 to 160 of about 90,246 (309)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
, 2011 The aerodynamical global optimization (GO) of the shape of a flying configuration (FC) leads to an extended variational problem with free boundaries. An own evolutive iterative optimum-optimorum (OO) theory was developed in order to solve this enlarged variational problem inside of a class of admissible FCs, defined by some chosen ...
openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem +17 more
wiley +1 more source
Analytical and experimental study of the effects of wing-body aerodynamic interaction on space shuttle subsonic flutter [PDF]
The effects on flutter of the aerodynamic interaction between the space shuttle bodies and wing, 1/80th-scale semispan models of the orbiter wing, the complete shuttle and intermediate component combinations were tested in the NASA Langley Research ...
Chipman, R. R., Rauch, F. J.
core +1 more source
Bridging Biology and Engineering: Unsteady Aerodynamics and Biomimetic Design of Micro Air Vehicles. [PDF]
Biomimetics (Basel)Prisăcariu EG, Dumitrescu O.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi +8 more
wiley +1 more source
Investigation of real-gas and viscous effects on the aerodynamic characteristics of a 40 deg half-cone with suggested correlations for the shuttle orbiter [PDF]
Parameters were evaluated that might be used to correlate shuttle orbiter aerodynamic data to be used in extrapolating from wind-tunnel to flight conditions.
Hunt, J. L., Jones, R. A., Woods, W. C.
core +1 more source
Aerodynamic performance optimization of the archimedes spiral wind turbine: combined experimental and CFD analysis of step ratio and blade number effects. [PDF]
Sci RepFaisal AE +5 more
europepmc +1 more source