Results 41 to 50 of about 635,092 (276)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Aerodynamic-Parameter Identification and Attitude Control of Quad-Rotor Model with CIFER and Adaptive LADRC

open access: yesChinese Journal of Mechanical Engineering, 2021
Current research on quadrotor modeling mainly focuses on theoretical analysis methods and experimental methods, which have problems such as weak adaptability to the environment, high test costs, and long durations. Additionally, the PID controller, which
Sen Yang   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Aerodynamic noise from a train pantograph

open access: yes, 2014
Many studies have shown that when the speed of high speed trains exceeds around 300km/h, aerodynamic noise becomes the most significant noise source. The pantograph, or current collector, is mounted on the top of the train and is therefore not shielded ...
Liu, Xiaowan   +3 more
core   +1 more source

Investigation of a Vertically Offset Rear-Rotor Quadrotor Configuration for Aerodynamic Interference Mitigation

open access: yesDrones
The deployment of multi-rotor drones in applications such as package delivery and urban air mobility is increasingly prevalent. Aerodynamic interference between rotors in traditional quadrotor drones impairs performance, and vertical offset is a ...
He Zhu   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Wake dynamics and rotor-fuselage aerodynamic interactions [PDF]

open access: yes, 2009
The unsteady loads experienced by a helicopter are known to be strongly influenced by aerodynamic interactions between the rotor and fuselage; these unsteady loads can lead to deficiencies in handling qualities and unacceptable vibratory characteristics ...
Brown, R.E., Kenyon, A.R.
core   +4 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Design Variable Effects and Flow Characteristics of High-Altitude Contra-Rotating Propellers for Long-Endurance UAVs

open access: yesDrones
To enhance the propulsion efficiency of near-space high-altitude unmanned aerial vehicle under low-density conditions and to gain a deeper understanding of the aerodynamic characteristics of contra-rotating propellers under complex interference, this ...
Wanli Chen   +3 more
doaj   +1 more source

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