Results 141 to 150 of about 39,978 (316)
Study of a Flexible UAV Proprotor [PDF]
, 2013 This paper is concerned with the evaluation of design techniques, both for the propulsive performance and for the structural behavior of a composite flexible proprotor.
Moschetta, Jean-Marc +5 more
core
Modelling the aerodynamics of vertical-axis wind turbines in unsteady wind conditions
, 2013 Most numerical and experimental studies of the performance of vertical-axis wind turbines have been conducted with the rotors in steady, and thus somewhat artificial, wind conditions - with the result that turbine aerodynamics, under varying wind ...
Scheurich, Frank, Brown, Richard
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Analysis of aerodynamic characteristics of hypersonic folding-wing aircraft
Hangkong gongcheng jinzhanHypersonic aircraft encounter challenges in adapting to complex external environments during missions. Conventional fixed-wing aircraft have limited optimal aerodynamic performance under specific conditions.
WU Zaoping, QIN Jian, WU Jie
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Suppression of stall on high-camber flap using upper-surface blowing [PDF]
, 2011 For many years, high-lift devices of an aeroplane have been employed to enhancing the aerodynamic performance of the wing during take-off and landing. But their complex geometries not only increase the design and manufacture cost, but also result in ...
Fang, Li
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
, 2013 The creation of an integrated rotorcraft conceptual and preliminary design framework at DLR involved the development of geometry and fuselage aerodynamics modules at the Institute of Aerodynamics and Flow Technology.
Kunze, Philipp
core
Optimal design of a flying-wing aircraft inner wing structure configuration [PDF]
, 2012 Flying-wing aircraft are considered to have great advantages and potentials in aerodynamic performance and weight saving. However, they also have many challenges in design.
Huang, Haidong
core