Results 121 to 130 of about 149,179 (315)

Efficient Adaptive Robust Aerodynamic Design Optimization Considering Uncertain Inflow Variations for a Diffusion Airfoil Across All Operating Incidences

Aerospace
The random fluctuations in inlet flow represent a common uncertainty in aero-engine compressors, necessitating the control of its effects through blade optimization design.
Zhengtao Guo, Lei Bao, Chaolong Li, Xianzhong Gao, Wuli Chu   +4 more
doaj   +1 more source

An effective approach for robust design optimization of wind turbine airfoils with random aerodynamic variables

Advances in Mechanical Engineering, 2019
The robust design optimization of an airfoil needs to continuously realize the probability-based aerodynamic simulation for various combinations of geometry and wind climate parameters.
Xufang Zhang, Zhenguang Wu, Wei He
doaj   +1 more source

Validation of a pair of computer codes for estimation and optimization of subsonic aerodynamic performance of simple hinged-flap systems for thin swept wings [PDF]

Extensive correlations of computer code results with experimental data are employed to illustrate the use of linearized theory attached flow methods for the estimation and optimization of the aerodynamic performance of simple hinged flap systems.
Carlson, Harry W., Darden, Christine M.
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Experimental Investigation of Aerodynamic Interaction in Non-Parallel Tandem Dual-Rotor Systems for Tiltrotor UAV

Drones
The distributed electric tilt-rotor Unmanned Aerial Vehicle (UAV) combines the vertical take-off and landing (VTOL) capability of helicopters with the high-speed cruise performance of fixed-wing aircraft, offering a transformative solution for Urban Air ...
He Zhu, Yuhao Du, Hong Nie, Zhiyang Xin, Xi Geng   +4 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Structural Feasibility of a Wind Turbine Blade Inspired by an Owl Airfoil

Energies
Geometrical solutions for aerodynamic limitations comprise a major development towards improving the wind energy capture efficiency and aerodynamic performance of wind turbines.
Dean Sesalim, Jamal Naser
doaj   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Optimum structural design with static aeroelastic constraints [PDF]

The static aeroelastic performance characteristics, divergence velocity, control effectiveness and lift effectiveness are considered in obtaining an optimum weight structure. A typical swept wing structure is used with upper and lower skins, spar and rib
Bowman, Keith B, Eastep, F. E., Grandhi, Ramana V.   +2 more
core   +1 more source

An evaluation of aerodynamics performance of a moving car with wind turbine system [PDF]

, 2014
This study presents a simulation result of an evaluation of the aerodynamic performance of a moving car with a wind turbine system. Sedan type cars (approaching the size of Proton Wira car) were modeled using the SolidWork software and simulation ...
Jamit, Rexca
core