Results 111 to 120 of about 16,262 (267)
Aerodynamic performance of autorotating seeds: scaling by size
Bioinspiration & BiomimeticsAbstract This study investigates the aerodynamics of a bio-inspired samara seed through high-fidelity numerical simulations, employing an overset mesh method to fully resolve its six-degree-of-freedom (6-DOF) motion. Coupled fluid and rigid body dynamics was solved using OpenFOAM v2406.
Alberto Lolli +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Corrugated surface microparticles with chitosan and levofloxacin for improved aerodynamic performance. [PDF]
Asian J Pharm Sci, 2023 Han CS +6 more
europepmc +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Chengshi guidao jiaotong yanjiuObjectiveThe enclosure condition of undercarriage equipment directly affects the aerodynamic shape of the train, which in turn affects the aerodynamic performance of the whole train. Therefore, it is necessary to carry out a research on the impact of the
Keming SHANG +4 more
doaj +1 more source
Aspect Ratio Effects on the Aerodynamic Performance of a Biomimetic Hummingbird Wing in Flapping. [PDF]
Biomimetics (Basel), 2023 Min Y, Zhao G, Pan D, Shao X.
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
A comparative examination of the aerodynamic performance of various seashell-shaped wind turbines. [PDF]
Heliyon, 2023 Hamid H, Abd El Maksoud RM.
europepmc +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source