Results 91 to 100 of about 21,740 (297)
On ionospheric aerodynamics [PDF]
Progress in Aerospace Sciences, 1975 Abstract This paper presents theoretical methods to determine the gas dynamic and the electrostatic effects due to the interaction caused by a rapidly moving body in the ionosphere. The principles of the methods are derived from the kinetic theory of collision-free plasma. It is shown that the collective behavior of the collision-free plasma makes it
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Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
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Discussion: “An Analysis of Axial Compressor Cascade Aerodynamics: Parts I and II” (Mellor, G. L., 1959, ASME J. Basic Eng., 81, pp. 362–377 and pp. 379–386) [PDF]
, 1959 N. Scholz
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Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
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Recent research results in the aerodynamics of supersonic vehicles. [PDF]
, 1966 A. W. Robins, O. A. Morris, R. V. Harris
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Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
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Calculation and uncertainty analysis method for airfoil drag coefficient considering compressibility
AIP AdvancesIn order to meet the need of evaluating the effectiveness of airfoil drag reduction design, the calculation and uncertainty analysis method for airfoil drag coefficient considering compressibility is studied.
Yufeng Du +4 more
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FluidsAn adaptive Free-Form Deformation parameterization method based on a spring analogy is presented for aerodynamic shape optimization problems. The proposed method effectively incorporates the gradients of the objective and constraint functions, achieving ...
Jinxin Zhou +3 more
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