Results 21 to 30 of about 2,957 (188)

Sensitivity of Polarized Epithelial Cells to the Pore-Forming Toxin Aerolysin [PDF]

Infection and Immunity, 2003
ABSTRACT Aerolysin is one of the major virulence factors produced by Aeromonas hydrophila , a human pathogen that produces deep wound infection and gastroenteritis. The toxin interacts with target mammalian cells by binding to the glycan core of glycosylphosphatidyl inositol (GPI)-anchored proteins and ...
Abrami, L., Fivaz, M., Glauser, P. E., Sugimoto, N., Zurzolo, C., van der Goot, F. G.   +5 more
openaire   +6 more sources

Exploring New Nanopore Sensors from the Aerolysin Family

Small
Abstract Aerolysin‐like proteins are a family of pore‐forming toxins with potential biotechnological applications as nanopore sensors for biomolecular detection and sequencing. Despite their conserved structural fold, the low sequence identity complicates sequence alignment, limiting the understanding of their ...
Bada Juarez, Juan F, Cirauqui, Nuria, Meireles, Fernando Augusto T P, Perrin, Louis Willem, Barry, Julian, Bokori-Brown, Monika, Marcaida, Maria J, Cao, Chan, Dal Peraro, Matteo   +8 more
openaire   +4 more sources

Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores [PDF]

Nature Communications, 2019
Aerolysin pores have potential to improve the accuracy of DNA sequencing and single-molecule proteomics. Here, the authors rationally design a set of mutated pores to achieve a more accurate detection of peptides and nucleic acids.
Chan Cao, Nuria Cirauqui, Maria Jose Marcaida, Elena Buglakova, Alice Duperrex, Aleksandra Radenovic, Matteo Dal Peraro   +6 more
doaj   +2 more sources

Pelacakan Gen Aerolysin dari Aeromonas hydrophila pada Ikan Mas yang Diberi Pakan Ekstrak Bawang Putih (DETECTION OF AEROLYSIN GEN FROM AEROMONAS HYDROPHILA IN COMMON CARP FED WITH GARLIC EXTRACT)

Jurnal Veteriner, 2014
Aeromonas hydrophila is a gram negative and opportunistic bacteria, which could cause fish mortalityin a short time from 80%-100%. One virulent factor of A. hydrophila on common carp (Cyprinus carpio L)that could cause fish mortality is aerolysin.
Iesje Lukistyowati, Kurniasih .
doaj   +1 more source

Mapping the sensing spots of aerolysin for single oligonucleotides analysis [PDF]

Nature Communications, 2018
Nanopores are an emerging powerful single-molecule method of DNA sequencing. Here the authors map the structure of aerolysin for use as a nanopore and show detection of modified and unmodified nucleobases.
Chan Cao, Meng-Yin Li, Nuria Cirauqui, Ya-Qian Wang, Matteo Dal Peraro, He Tian, Yi-Tao Long   +6 more
doaj   +4 more sources

Genomic Characterization of Aeromonas dhakensis Isolated From a Fatal Dolphin Case. [PDF]

Environ Microbiol Rep
Comparative genomic analysis of an Aeromonas dhakensis isolate recovered from a fatal dolphin case revealed close relatedness to previously described strains and a broadly comparable virulence‐associated gene profile, including rtxA, with no isolate‐specific virulence‐associated annotations identified.
Yamazaki K, Takahashi Y, Yoneda Y, Kashimoto T, Kakuda T.   +4 more
europepmc   +2 more sources

USES OF AEROLYSIN NANOPORES

The invention relates to use of an aerolysin nanopore for the discrimination of different protein isoforms bearing different post-translational modifications (PTMs) and to methods for detecting adverse medical conditions associated with the presence of ...
CAO CHAN, DAL PERARO MATTEO, LASHUEL HILAL   +2 more
openaire   +2 more sources

Sub-Nanomolar Detection and Discrimination of Microcystin Congeners Using Aerolysin Nanopores. [PDF]

ACS Nano
Climate-driven disruptions in aquatic ecosystems are amplifying cyanotoxin production, threatening drinking and recreational water safety. Monitoring of these toxins is challenged by requirements of the low μg/L detection limits and structural diversity.
Agerova A, Bada Juarez JF, Perrin LW, Abriata LA, Marcaida MJ, Carratalà A, Selmani N, Barbier S, Khajehnouri F, Vassalli G, Janssen EML, Cao C, Kohn T, Dal Peraro M.   +13 more
europepmc   +3 more sources

Inhibitory Effect of Polydatin Against Aeromonas hydrophila Infections by Reducing Aerolysin Production

Frontiers in Veterinary Science, 2022
The fast-growing demand for aquatic products has led to the rapid development of aquaculture. However, diseases caused by bacterial pathogens result in severe economic losses all over the world.
Jing Dong, Tianhui Yan, Qiuhong Yang, Shun Zhou, Yi Song, Yongtao Liu, Liang Ma, Ning Xu, Yibin Yang, Xiaohui Ai   +9 more
doaj   +1 more source

Use of black soldier fly (Hermetia illucens) prepupae amino acids as anti Aeromonas hydrophila enterotoxin in vivo [PDF]

Iraqi Journal of Veterinary Sciences, 2023
Aeromonas hydrophila is an opportunistic freshwater. These bacteria cause gastroenteritis and septicemia in animals and humans. Hemolysin and aerolysin, are important in the pathogenesis of A. hydrophila.
Dahliatul Qosimah, Sanarto Santosa, Maftuch Maftuch, Husnul Khotimah, Loeki Enggar Fitri, Aulanni am Aulanni am   +5 more
doaj   +1 more source